Extracellular Heat Shock Protein 90 Alpha (eHsp90α)'s Role in Cancer Progression and the Development of Therapeutic Strategies

TS Reynolds, BSJ Blagg - European Journal of Medicinal Chemistry, 2024 - Elsevier
Heat shock protein 90 alpha (Hsp90α) is an abundantly expressed and evolutionarily
conserved molecular chaperone. Hsp90α is the inducible Hsp90 isoform, and its expression …

GW4869 Can Inhibit Epithelial-Mesenchymal Transition and Extracellular HSP90α in Gefitinib-Sensitive NSCLC Cells

X Wan, Y Fang, J Du, S Cai, H Dong - OncoTargets and Therapy, 2023 - Taylor & Francis
Objective GW4869 is an exosomal inhibitor. It is necessary to delay the occurrence of
gefitinib resistance during non-small-cell lung cancer (NSCLC) treatment. This study aimed …

Hsp90α and cell death in cancers: a review

B Liu, D Qian - Discover Oncology, 2024 - Springer
Heat shock protein 90α (Hsp90α), an important molecular chaperone, plays a crucial role in
regulating the activity of various intracellular signaling pathways and maintaining the …

eHSP90α in front-line therapy in EGFR exon 19 deletion and 21 Leu858Arg mutations in advanced lung adenocarcinoma

Y Bian, H Liu, J Huang, Z Feng, Y Lin, J Li, L Zhang - BMC cancer, 2024 - Springer
Purpose Extracellular heat shock protein 90 AA1 (eHSP90α) is intricately linked to tumor
progression and prognosis. This study aimed to investigate the difference in the value of …

The critical role of serum thymidine kinase 1 (STK1) in predicting prognosis for immunotherapy in T4 stage lung squamous cell carcinoma

J Pan, H Liu, S Li, W Wei, J Mai, Y Bian, S Ning, J Li… - Heliyon, 2023 - cell.com
Purpose The role of serum thymidine kinase 1 (STK1) in predicting the prognosis of T4-
stage lung squamous cell carcinoma (LUSC) with immunotherapy is the focus of our work …

Targeting MDSC-mediated immunosuppression in melanoma

FG Özbay Kurt - 2023 - archiv.ub.uni-heidelberg.de
Immunotherapeutic strategies for malignant melanoma have made significant progress but
are still challenged by the development of resistance in a subset of patients. One of the …

[PDF][PDF] obtaining the doctoral degree

MSFGÖ Kurt - scholar.archive.org
Immunotherapeutic strategies for malignant melanoma have made significant progress but
are still challenged by the development of resistance in a subset of patients. One of the …

[引用][C] Targeting MDSC-mediated immunosuppression in melanoma

Ö Kurt, F Gül - 2023 - Dissertation, Heidelberg, Universität …