Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass
loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) …

Muscle atrophy and decline in muscle strength appear very rapidly with prolonged disuse or
mechanical unloading after acute hospitalization or experimental bed rest. The current study …

While the benefits of physical exercise for a healthy aging are well-recognized, a growing
body of evidence shows that sedentary behavior has deleterious health effects …

The ever increasing burden of an aging population and pandemic of metabolic syndrome
worldwide demands further understanding of the modifiable risk factors in reducing disability …

Physical inactivity (PI) is a major risk factor of chronic diseases. A major aspect of PI is loss
of muscle mass and strength. The latter phenomenon significantly impacts daily life and …

Identification of cost-effective interventions to maintain muscle mass, muscle strength, and
physical performance during muscle wasting and aging is an important public health …

Skeletal muscle is the most abundant tissue in healthy individuals and it has important roles
in health beyond voluntary movement. The overall mass and energy requirements of …

Spaceflight causes muscle wasting. The Sarcolab pilot study investigated two astronauts
with regards to plantar flexor muscle size, architecture, and function, and to the underlying …

Aging is widespread worldwide and a significant risk factor for cardiovascular disease
(CVD). Mechanisms underlying aging have attracted considerable attention in recent years …

Purpose This study aimed to non-invasively test the hypothesis that (a) short-term lower limb
unloading would induce changes in the neural control of force production (based on motor …