Prostacyclin (PGI2) is a member of the prostanoid group of eicosanoids that regulate
homeostasis, hemostasis, smooth muscle function and inflammation. Prostanoids are …

The Barker hypothesis asserts that stressful events early in the life history of an individual
have negative health consequences later in adulthood. The hypothesis initially focused on …

Maternal and child undernutrition and micronutrient deficiencies affect approximately half of
the world's population. These conditions include intrauterine growth restriction (IUGR), low …

Preeclampsia is defined as new-onset hypertension with proteinuria after 20 wk gestation
and is hypothesized to be due to shallow trophoblast invasion in the spiral arteries thus …

Liquid chromatography tandem mass spectrometry is one of the most specific techniques
available in clinical laboratories. In the past, immunoassays were the primary methodology …

Hypoxia may influence normal and different pathological processes. Low oxygenation
activates a variety of responses, many of them regulated by hypoxia‐inducible factor 1 …

Hypertension is one of the cardiovascular diseases that might cause cardiovascular
remodeling and endothelial dysfunction besides high blood pressure. Angiotensin II (Ang II) …

Aims Intrauterine growth restriction (IUGR), a condition affecting 7–15% of all pregnancies,
is associated with an increased mortality rate during adulthood. Several animal models have …

The “developmental origins of health and disease”(DOHAD) hypothesis derives from clinical
observations, indicating long-term health consequences for persons of low birth weight …

Preeclampsia (PE) is a pregnancy-induced hypertension with proteinuria that typically
develops after 20 weeks of gestation. A reduction in uterine blood flow causes placental …