Background The implication of gut microbiota in the control of brain functions in health and
disease is a novel, currently emerging concept. Accumulating data suggest that the gut …

The gut microbiota and their metabolites could play an important role in health and diseases
of human beings. Short-chain fatty acids (SCFAs) are mainly produced by gut microbiome …

The intestinal immune system interacts with commensal microbiota to maintain gut
homeostasis. Furthermore, stress alters the microbiome composition, leading to impaired …

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related death worldwide. It involves the complex interactions between genetic …

Human health is determined by the interaction of our environment with the genome,
epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic …

Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

Objective The extent to which tryptophan (Trp) metabolism alterations explain or influence
the outcome of inflammatory bowel diseases (IBDs) is still unclear. However, several Trp …

In inflammatory bowel disease (IBD), intestinal mucosa cell and intestinal epithelial cell are
severely damaged, and then their susceptibility to bacteria increases, so many commensal …

Gut microbiota was only considered as a commensal organism that aids in digestion, but
recent studies revealed that the microbiome play a critical role in both physiological and …

The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial
metabolites and their availability in the gut and other organs is determined by environmental …