Short-chain fatty acids alleviate vancomycin-caused humoral immunity attenuation in rabies-vaccinated mice by promoting the generation of plasma cells via Akt …

Q Wu, Y Zhang, C Wang, Y Hou, W He, L Wang… - Journal of …, 2023 - Am Soc Microbiol
Mounting evidence suggests that gut microbial composition and its metabolites, including
short-chain fatty acids (SCFAs), have beneficial effects in regulating host immunogenicity to …

Three layers of intestinal γδ T cells talk different languages with the microbiota

F Rampoldi, I Prinz - Frontiers in Immunology, 2022 - frontiersin.org
The mucosal surfaces of our body are the main contact site where the immune system
encounters non-self molecules from food-derived antigens, pathogens, and symbiotic …

Gut-immune axis and cardiovascular risk in chronic kidney disease

F Behrens, H Bartolomaeus, N Wilck… - Clinical Kidney …, 2024 - academic.oup.com
Patients with chronic kidney disease (CKD) suffer from marked cardiovascular morbidity and
mortality, so lowering the cardiovascular risk is paramount to improve quality of life and …

The vitamin B5/coenzyme A axis: a target for immunomodulation?

R Miallot, V Millet, F Galland… - European Journal of …, 2023 - Wiley Online Library
Coenzyme A (CoA) serves as a vital cofactor in numerous enzymatic reactions involved in
energy production, lipid metabolism, and synthesis of essential molecules. Dysregulation of …

Alterations and potential applications of gut microbiota in biological therapy for inflammatory bowel diseases

D Pu, Z Zhang, B Feng - Frontiers in Pharmacology, 2022 - frontiersin.org
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a
chronic immune-mediated inflammatory disorder of the gastrointestinal tract that is closely …

Current updates on metabolites and its interlinked pathways as biomarkers for diabetic kidney disease: a systematic review

S Das, D Rajeswari, G Venkataraman, R Elumalai… - Translational …, 2023 - Elsevier
Diabetic kidney disease (DKD) is a major microvascular complication of diabetes mellitus
(DM) that poses a serious risk as it can lead to end-stage renal disease (ESRD). DKD is …

A binary module for microbiota-mediated regulation of γδ17 cells, hallmarked by microbiota-driven expression of programmed cell death protein 1

HI Huang, Y Xue, ML Jewell, CY Tan, B Theriot… - Cell reports, 2023 - cell.com
Little is known about how microbiota regulate innate-like γδ T cells or how these restrict their
effector functions within mucosal barriers, where microbiota provide chronic stimulation …

The role of gut microbiota and metabolites in regulating the immune response in drug-induced enteritis

Y Chen, Z Wang, X Chen, G Chao… - Journal of Applied …, 2023 - academic.oup.com
Drug-induced enteritis is an inflammatory disease changing in the morphology and function
of the intestine as a result of medicine damage. With the increase in drug abuse in recent …

Propionate functions as a feeding state–dependent regulatory metabolite to counter proinflammatory signaling linked to nutrient load and obesity

K Han, AM Meadows, MJ Rodman… - Journal of Leukocyte …, 2024 - academic.oup.com
Generally, fasting and refeeding confer anti-and proinflammatory effects, respectively. In
humans, these caloric-load interventions function, in part, via regulation of CD4+ T cell …

Nutrients, herbal bioactive derivatives and commensal microbiota as tools to lower the risk of SARS-CoV-2 infection

A Romani, D Sergi, E Zauli, R Voltan, G Lodi… - Frontiers in …, 2023 - frontiersin.org
The SARS-CoV-2 outbreak has infected a vast population across the world, causing more
than 664 million cases and 6.7 million deaths by January 2023. Vaccination has been …