3D genomic mapping reveals multifocality of human pancreatic precancers

AM Braxton, AL Kiemen, MP Grahn, A Forjaz… - Nature, 2024 - nature.com
Pancreatic intraepithelial neoplasias (PanINs) are the most common precursors of
pancreatic cancer, but their small size and inaccessibility in humans make them challenging …

TM6SF1 通过抑制KRAS-MEK-ERK 信号通路影响肝内胆管癌细胞的生物学行为

陈顺琦, 刘信燚, 曾涛, 刘梦玉, 王玉婷, 辛海贝… - 中国癌症防治 …, 2024 - zgazfz.com
目的探究六次跨膜蛋白1 (transmembrane 6 superfamily member 1, TM6SF1) 在肝内胆管癌(
intrahepatic cholangiocarcinoma, iCCA) 中的生物学行为及其作用机制. 方法收集2008 年8 …