Identification and characterization of Sofosbuvir‐resistant mutations of hepatitis C virus genotype 3a replicon

JW Ngari, S Leumi, L Han, C Liu… - Journal of Medical …, 2023 - Wiley Online Library
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide. Among
its 8 genotypes (GT), GT3 has a relatively lower sustained virological response to highly …

丙型肝炎病毒非结构蛋白5B 聚合酶抑制剂的研究进展

韩迪, 薛艺伟, 刘风祥, 展鹏, 徐永涛 - 药学进展, 2024 - pps.cpu.edu.cn
丙型肝炎病毒(hepatitis C virus, HCV) 感染是全球范围内的健康挑战. 该病毒的非结构蛋白5B
(non-structuralprotein 5B, NS5B) 聚合酶对其RNA 的复制起到了关键作用, 是抗HCV …

Progress of Hepatitis C Virus Non-structural Protein 5B Polymerase Inhibitors

HAN Di, XUE Yiwei, LIU Fengxiang, Z Peng… - Progress in …, 2024 - pps.cpu.edu.cn
Hepatitis C virus (HCV) infection is a worldwide health challenge. The non-structural protein
5B (NS5B) polymerase of the virus plays a key role in its RNA replication and is a key target …