Genetic determinants and cellular constraints in noisy gene expression
In individual cells, transcription is a random process obeying single-molecule kinetics. Often,
it occurs in a bursty, intermittent manner. The frequency and size of these bursts affect the …
it occurs in a bursty, intermittent manner. The frequency and size of these bursts affect the …
Modulation of chemical composition and other parameters of the cell at different exponential growth rates
H Bremer, PP Dennis - Ecosal plus, 2008 - Am Soc Microbiol
This review begins by briefly presenting the history of research on the chemical composition
and other parameters of cells of E. coli and S. enterica at different exponential growth rates …
and other parameters of cells of E. coli and S. enterica at different exponential growth rates …
[HTML][HTML] Growth rate-dependent global effects on gene expression in bacteria
Bacterial gene expression depends not only on specific regulatory mechanisms, but also on
bacterial growth, because important global parameters such as the abundance of RNA …
bacterial growth, because important global parameters such as the abundance of RNA …
General properties of transcriptional time series in Escherichia coli
Gene activity is described by the time series of discrete, stochastic mRNA production events.
This transcriptional time series shows intermittent, bursty behavior. One consequence of this …
This transcriptional time series shows intermittent, bursty behavior. One consequence of this …
Transcriptional interference–a crash course
KE Shearwin, BP Callen, JB Egan - TRENDS in Genetics, 2005 - cell.com
The term 'transcriptional interference'(TI) is widely used but poorly defined in the literature.
There are a variety of methods by which one can interfere with the process or the product of …
There are a variety of methods by which one can interfere with the process or the product of …
Mechanism of regulation of transcription initiation by ppGpp. I. Effects of ppGpp on transcription initiation in vivo and in vitro
To determine the role of ppGpp in both negative and positive regulation of transcription
initiation during exponential growth in Escherichia coli, we examined transcription in …
initiation during exponential growth in Escherichia coli, we examined transcription in …
Functional reconstitution of a bacterial CO2 concentrating mechanism in Escherichia coli
Many photosynthetic organisms employ a CO2 concentrating mechanism (CCM) to increase
the rate of CO2 fixation via the Calvin cycle. CCMs catalyze≈ 50% of global photosynthesis …
the rate of CO2 fixation via the Calvin cycle. CCMs catalyze≈ 50% of global photosynthesis …
RETRACTED ARTICLE: Strategies for efficient production of heterologous proteins in Escherichia coli
S Jana, JK Deb - Applied microbiology and biotechnology, 2005 - Springer
In recent years, the number of recombinant proteins used for therapeutic applications has
increased dramatically. Production of these proteins has a remarkable demand in the …
increased dramatically. Production of these proteins has a remarkable demand in the …
A 'resource allocator'for transcription based on a highly fragmented T7 RNA polymerase
Synthetic genetic systems share resources with the host, including machinery for
transcription and translation. Phage RNA polymerases (RNAP s) decouple transcription from …
transcription and translation. Phage RNA polymerases (RNAP s) decouple transcription from …
Few regulatory metabolites coordinate expression of central metabolic genes in Escherichia coli
K Kochanowski, L Gerosa, SF Brunner… - Molecular Systems …, 2017 - embopress.org
Transcription networks consist of hundreds of transcription factors with thousands of often
overlapping target genes. While we can reliably measure gene expression changes, we still …
overlapping target genes. While we can reliably measure gene expression changes, we still …