[HTML][HTML] Extracellular vesicles: The next generation in gene therapy delivery
Extracellular vesicles (EVs) are esteemed as a promising delivery vehicle for various genetic
therapeutics. They are relatively inert, non-immunogenic, biodegradable, and …
therapeutics. They are relatively inert, non-immunogenic, biodegradable, and …
Exosomes based strategies for brain drug delivery
Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
[HTML][HTML] Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte
J Jin, Y Shi, J Gong, L Zhao, Y Li, Q He… - Stem cell research & …, 2019 - Springer
Background It is confirmed that adipose-derived stem cells (ADSCs) transplantation
effectively relieves kidney fibrosis and type 2 diabetes disease in mice. Currently, exosome …
effectively relieves kidney fibrosis and type 2 diabetes disease in mice. Currently, exosome …
Preservation and storage stability of extracellular vesicles for therapeutic applications
Abstract Recently, extracellular vesicles (EVs)—including exosomes, microvesicles, and
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …
Exosomes in cancer nanomedicine and immunotherapy: prospects and challenges
Exosomes (versatile, cell-derived nanovesicles naturally endowed with exquisite target-
homing specificity and the ability to surmount in vivo biological barriers) hold substantial …
homing specificity and the ability to surmount in vivo biological barriers) hold substantial …
[HTML][HTML] A call for the standardised reporting of factors affecting the exogenous loading of extracellular vesicles with therapeutic cargos
Extracellular vesicles (EVs) are complex nanoparticles required for the intercellular transfer
of diverse biological cargoes. Unlike synthetic nanoparticles, EVs may provide a natural …
of diverse biological cargoes. Unlike synthetic nanoparticles, EVs may provide a natural …
[HTML][HTML] Improved loading of plasma-derived extracellular vesicles to encapsulate antitumor miRNAs
MAC Pomatto, B Bussolati, S D'Antico, S Ghiotto… - … Therapy-Methods & …, 2019 - cell.com
Extracellular vesicles (EVs) carry various molecules involved in intercellular communication
and have raised great interest as drug delivery systems. Several engineering methods have …
and have raised great interest as drug delivery systems. Several engineering methods have …
[HTML][HTML] Therapeutic miRNA-enriched extracellular vesicles: current approaches and future prospects
Extracellular vesicles (EVs) are 50–300 nm vesicles secreted by eukaryotic cells. They can
carry cargo (including miRNA) from the donor cell to the recipient cell. miRNAs in EVs can …
carry cargo (including miRNA) from the donor cell to the recipient cell. miRNAs in EVs can …
Exosome-mediated delivery of RNA and DNA for gene therapy
Gene therapy promises to revolutionize biomedicine and personalized medicine by
modulating or compensating the expression of abnormal genes. The biggest obstacle for …
modulating or compensating the expression of abnormal genes. The biggest obstacle for …
Milk/colostrum exosomes: A nanoplatform advancing delivery of cancer therapeutics
Chemotherapeutics continue to play a central role in the treatment of a wide variety of
cancers. Conventional chemotherapy involving bolus intravenous doses results in severe …
cancers. Conventional chemotherapy involving bolus intravenous doses results in severe …