Background Gastric cancer necessitates novel treatments, and exosomes are promising
therapeutic carriers. We created miR-494-3p inhibitor exosomes to assess their effects on …

Renal cell carcinoma (RCC) is the most common type of kidney cancer that accounts for
approximately 2–3% of adult malignancies. Among the primary treatment methods for this …

The adenosine concentration and forkhead box protein (Foxp3) expression in T regulatory
cells (T regs) are increased during sepsis. However, the mechanism by which adenosine …

Background Microcirculation is important for regulating ischemia-reperfusion (I/R) injury
associated with skin flap transplantation surgery. We investigated whether co-culture with …

Wound healing of the oral and maxillofacial area affects the quality of life and mental health
of the patient; therefore, effective therapies are required to promote wound healing …

核酸类药物是在基因水平上发挥作用的RNA 或DNA。 目前应用较多的有核酸适配体、
反义寡核苷酸、 信使RNA、 微RNA、 小干扰RNA、 小激活RNA 等。 核酸类药物临床应用面临 …

Reactive oxygen species are known to be involved in various diseases, and antioxidant
ingredients are expected to essentially prevent diseases and contribute to improving health …

Clinical translation of gene therapy has been challenging, due to limitations in current
delivery vehicles such as traditional viral vectors. Herein, we report the use of gRNA: Cas9 …

Extracellular vesicles (EVs) have emerged as key mediators of intercellular communication
and consequently have the potential to be potent therapeutic vectors. Beyond their …

All eukaryotic cells release nanosized extracellular vesicles, or nEV, into the extracellular
spaces. They have been found in various bodily fluids and are critical as intercellular …