[HTML][HTML] Stem cell-derived extracellular vesicles in the therapeutic intervention of Alzheimer's Disease, Parkinson's Disease, and stroke
W Zhou, X Wang, Y Dong, P Gao, X Zhao, M Wang… - Theranostics, 2024 - ncbi.nlm.nih.gov
With the increase in the aging population, the occurrence of neurological disorders is rising.
Recently, stem cell therapy has garnered attention due to its convenient sourcing, minimal …
Recently, stem cell therapy has garnered attention due to its convenient sourcing, minimal …
Non-pigmented ciliary epithelium-derived extracellular vesicles loaded with smad7 sirna attenuate wnt signaling in trabecular meshwork cells in vitro
S Tabak, V Feinshtein, S Schreiber-Avissar… - Pharmaceuticals, 2021 - mdpi.com
Primary open-angle glaucoma is established by the disruption of trabecular meshwork (TM)
function. The disruption leads to increased resistance to the aqueous humor (AH) …
function. The disruption leads to increased resistance to the aqueous humor (AH) …
Therapeutic application of small extracellular vesicles (sEVs): pharmaceutical and pharmacokinetic challenges
Y Takakura, A Matsumoto… - Biological and …, 2020 - jstage.jst.go.jp
Small extracellular vesicles (sEVs), including exosomes as typical example, are cell-derived
vesicles comprising lipid bilayer with a diameter approximately 100 nm. sEVs are …
vesicles comprising lipid bilayer with a diameter approximately 100 nm. sEVs are …
Extracellular nanovesicles: from intercellular messengers to efficient drug delivery systems
Nanosized extracellular vesicles (nEV) are released by all the eukaryotic cells into the
extracellular spaces. They serve as crucial mediators of intercellular communication, and …
extracellular spaces. They serve as crucial mediators of intercellular communication, and …
Exosomes as new generation vehicles for drug delivery systems
N Dilsiz - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Exosomes are the smallest subtype of mobile extracellular vesicles (EVs), and round sacs
with a diameter between 30 and 120 nm are released by almost all cell types into the …
with a diameter between 30 and 120 nm are released by almost all cell types into the …
Advancement in exosome-based cancer therapeutics: A new era in cancer treatment
A Dutta, S Paul - Frontiers in Nanotechnology, 2022 - frontiersin.org
In the modern era of rapid development and advancement in cancer therapeutics and
management, there is a growing awareness in the application of exosomes as a potential …
management, there is a growing awareness in the application of exosomes as a potential …
Effective exosomes in breast cancer: Focusing on diagnosis and treatment of cancer progression
B Abdullaev, SA Rasyid, E Ali, AMB Al-Dhalimy… - … -Research and Practice, 2023 - Elsevier
Breast cancer (BC) is the most prevalent aggressive malignant tumor in women worldwide
and develops from breast tissue. Although cutting-edge treatment methods have been used …
and develops from breast tissue. Although cutting-edge treatment methods have been used …
Engineering of exosomes: steps towards green production of drug delivery system
AY Sherif, GI Harisa, FK Alanazi… - Current Drug …, 2019 - ingentaconnect.com
Targeting of therapeutic agents to their specific site of action not only increases the treatment
efficacy, but also reduces systemic toxicity. Therefore, various drug delivery systems (DDSs) …
efficacy, but also reduces systemic toxicity. Therefore, various drug delivery systems (DDSs) …
Harnessing the therapeutic potential of extracellular vesicles for cancer treatment
Y Zhang, Y Xiao, G Sun, X Jin, L Guo, T Li… - Seminars in Cancer …, 2021 - Elsevier
Cancer therapeutic strategies include surgeries, radiotherapy, chemotherapy, targeted
therapy and immunotherapies. However, current cancer treatment still faces challenges …
therapy and immunotherapies. However, current cancer treatment still faces challenges …
Small extracellular vesicles loaded with immunosuppressive miRNAs leads to an inhibition of dendritic cell maturation
L Czernek, Ł Pęczek, M Düchler - Archivum Immunologiae et Therapiae …, 2022 - Springer
In particular conditions, inhibition of an immune response is required to prevent tissue
damage. Among these conditions are diseases caused by an over-reactive immune …
damage. Among these conditions are diseases caused by an over-reactive immune …