[HTML][HTML] Benzimidazole-based schiff base hybrid scaffolds: a promising approach to develop multi-target drugs for alzheimer's disease
A series of benzimidazole-based Schiff base derivatives (1–18) were synthesized and
structurally elucidated through 1H NMR, 13C NMR and HREI-MS analysis. Subsequently …
structurally elucidated through 1H NMR, 13C NMR and HREI-MS analysis. Subsequently …
Hybrid molecules of thiadiazole-based benzothioate and benzenesulfonothioate: synthesis, structural analysis, and evaluation as potential inhibitors of thymidine …
The thiadiazole-based benzothioate (3a-f) and benzenesulfonothioate (5a-f) hybrid
derivatives were designed and synthesized in a single step reaction. All the synthesized …
derivatives were designed and synthesized in a single step reaction. All the synthesized …
Molecular modeling, synthesis, and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory activities of novel benzimidazole-bearing thiadiazole derivatives
A new series of benzimidazole-based thiadiazole hybrids analogues (6a–p) as effective
Alzheimer's inhibitors were synthesized and then evaluated for their inhibition profile against …
Alzheimer's inhibitors were synthesized and then evaluated for their inhibition profile against …
[HTML][HTML] Targeting disease with benzoxazoles: a comprehensive review of recent developments
A Abdullahi, KY Yeong - Medicinal Chemistry Research, 2024 - Springer
Benzoxazole is an attractive scaffold in medicinal chemistry due to its diverse biological
applications. From 2016 to 2023, a plethora of benzoxazole derivatives have been …
applications. From 2016 to 2023, a plethora of benzoxazole derivatives have been …
Synthesis, in Vitro Bio-Evaluation and in Silico Molecular Docking Studies of Thiadiazole-Based Schiff Base Derivatives
Aim: Recently, thiadiazole-containing drugs have gained greater clinical relevance and are
being explored for the development of new antidiabetic, antiurease and antimicrobial agents …
being explored for the development of new antidiabetic, antiurease and antimicrobial agents …
[HTML][HTML] Identification of Indazole-Based Thiadiazole-Bearing Thiazolidinone Hybrid Derivatives: Theoretical and Computational Approaches to Develop Promising …
A hybrid library of compounds based on indazole-based thiadiazole containing
thiazolidinone moieties (1–17) was synthesized. The synthesized compounds were …
thiazolidinone moieties (1–17) was synthesized. The synthesized compounds were …
Development of promising acetylcholinesterase and butyrylcholinesterase inhibitors: Synthesis, in vitro and in silico approaches of pyridine derived fused bis …
The present study aims to synthesize new thiadiazole/oxadiazole fused thiadiazole
derivatives, incorporating pyridine moiety as effective inhibitors of acetylcholinesterase …
derivatives, incorporating pyridine moiety as effective inhibitors of acetylcholinesterase …
In vitro and in silico correlation of bis-thiazole based Schiff base hybrids analogues: A computational approach develop to promising acetylcholinesterase and …
We have synthesized sixteen bis-thiazole based Schiff bases hybrid derivatives (1–16) and
evaluated against acetylcholinesterase and butyrylcholinesterase enzymes. All analogues …
evaluated against acetylcholinesterase and butyrylcholinesterase enzymes. All analogues …
Novel bis-thiazole-thiazolidinone hybrid derivatives: Synthesis, structural properties and anticholinesterase bioactive potential as drug competitor based on docking …
A total of sixteen new derivatives of the bis-thiazole-thiazolidinone skeletal structure were
synthesized and examined for their potential as inhibitors of cholinesterase in the context of …
synthesized and examined for their potential as inhibitors of cholinesterase in the context of …
Asymmetric Radical-Type 1, 2-Alkoxy-Sulfenylation of Benzoxazole-2-Thiols to Vinylarenes Catalyzed by Chiral Vanadyl Complexes
YH Liu, HY Tsui, PH Chien, CT Chen - ACS Catalysis, 2024 - ACS Publications
Chiral vanadyl complex derived from N-salicylidene-tert-butyl-l-glycinate bearing a 3-(2, 5-
dimethyl) phenyl-5-bromo substituent was first tested for the catalytic feasibility of …
dimethyl) phenyl-5-bromo substituent was first tested for the catalytic feasibility of …