Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

Nano‐immunotherapy has been recognized as a highly promising strategy for cancer
treatment in recent decades, which combines nanotechnology and immunotherapy to …

Transforming growth factor-β (TGF-β) signaling shows important roles in both physiology
and pathology, especially in the progression of inflammatory diseases including cancer …

Neutrophil extracellular traps (NETs) released by activated neutrophils typically consist of
DNA-histone complexes and granule proteins. NETs were originally identified as a host …

Tumor development and metastasis are closely related to the tumor microenvironment
(TME). Recently, several studies indicate that modulating TME can enhance cancer …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. The tumor
immune microenvironment (TIME) formed by interactions among cancer cells, immune cells …

Genetic and epigenetic alterations play central roles in shaping the immunosuppressive
tumor microenvironment (TME) to evade immune surveillance. The previous study shows …

With an understanding of immunity in the tumor microenvironment, immunotherapy turns out
to be a powerful tool in the clinic to treat many cancers. The strategies applied in cancer …

Metastasis, a primary cause of death in patients with malignancies, is promoted by intrinsic
changes in both tumor and non-malignant cells in the tumor microenvironment (TME). As …

Electrical stimulation is a promising technique for drug-free treatment of complex malignant
tumors because it can directly kill tumor cells and induce immunotherapy, avoiding the risk …