Biomarkers in pulmonary infections: a clinical approach

P Póvoa, L Coelho, JP Cidade, A Ceccato… - Annals of Intensive …, 2024 - Springer
Severe acute respiratory infections, such as community-acquired pneumonia, hospital-
acquired pneumonia, and ventilator-associated pneumonia, constitute frequent and lethal …

Beta-D-glucan in patients with haematological malignancies

M Mikulska, E Balletto, E Castagnola, A Mularoni - Journal of Fungi, 2021 - mdpi.com
(1-3)-beta-D-glucan (BDG) is an almost panfungal marker (absent in zygomycetes and most
cryptococci), which can be successfully used in screening and diagnostic testing in patients …

[HTML][HTML] Epidemiology of fungal diseases in Africa: A review of diagnostic drivers

F Bongomin, SA Fayemiwo - Current Medical Mycology, 2021 - ncbi.nlm.nih.gov
Background and Purpose: There has been a significant increase in the burden of fungal
diseases in the last few decades which has imposed a global threat to the health of humans …

Outbreak-Causing Fungi: Pneumocystis jirovecii

S Dellière, M Gits-Muselli, S Bretagne, A Alanio - Mycopathologia, 2020 - Springer
Pneumocystis jirovecii pneumonia (PCP) is an important cause of morbidity in
immunocompromised patients, with a higher mortality in non-HIV than in HIV patients. P …

Diagnosis of invasive fungal disease in coronavirus disease 2019: approaches and pitfalls

PL White - Current Opinion in Infectious Diseases, 2021 - journals.lww.com
Because of the vast numbers of COVID-19 infections, IFD in COVID-19 critical-care patients
represents a significant burden of disease, even if incidences are less than 5%. Optimal …

Diversity of Pneumocystis jirovecii during Infection Revealed by Ultra-Deep Pyrosequencing

A Alanio, M Gits-Muselli, S Mercier-Delarue… - Frontiers in …, 2016 - frontiersin.org
Pneumocystis jirovecii is an uncultivable fungal pathogen responsible for Pneumocystis
pneumonia (PCP) in immunocompromised patients, the physiopathology of which is only …

Critically ill patients with HIV: 40 years later

É Azoulay, N de Castro, F Barbier - Chest, 2020 - Elsevier
The development of combination antiretroviral therapies (cARTs) in the mid-1990s has
dramatically modified the clinical presentation of critically ill, HIV-infected patients. Most …

Advances in the diagnosis of fungal pneumonias

BT Kelly, KM Pennington, AH Limper - Expert review of respiratory …, 2020 - Taylor & Francis
Introduction Fungal infections are increasingly encountered in clinical practice due to more
favorable environmental conditions and increasing prevalence of immunocompromised …

Ability of quantitative PCR to discriminate Pneumocystis jirovecii pneumonia from colonization

T Perret, A Kritikos, PM Hauser… - Journal of medical …, 2020 - microbiologyresearch.org
Introduction. Pneumocystis jirovecii pneumonia (PCP) is a severe disease affecting
immunocompromised patients. Diagnosis is difficult due to the low sensitivity of direct …

A Negative (1,3)-β-D-Glucan Result Alone Is Not Sufficient to Rule Out a Diagnosis of Pneumocystis Pneumonia in Patients With Hematological Malignancies

C Damiani, B Demey, C Pauc, Y Le Govic… - Frontiers in …, 2021 - frontiersin.org
Background: Serum (1, 3)-β-D-glucan (BG) testing is increasingly being used in the
diagnostic armamentarium for invasive fungal diseases. Given its high sensitivity, some …