Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment

Q Yang, M Ciebiera, MV Bariani, M Ali… - Endocrine …, 2022 - academic.oup.com
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

Selective progesterone receptor modulators—mechanisms and therapeutic utility

MS Islam, S Afrin, SI Jones, J Segars - Endocrine Reviews, 2020 - academic.oup.com
Selective progesterone receptor modulators (SPRMs) are a new class of compounds
developed to target the progesterone receptor (PR) with a mix of agonist and antagonist …

Progesterone signaling and uterine fibroid pathogenesis; molecular mechanisms and potential therapeutics

M Ali, M Ciebiera, S Vafaei, S Alkhrait, HY Chen… - Cells, 2023 - mdpi.com
Uterine fibroids (UFs) are the most important benign neoplastic threat to women's health
worldwide, with a prevalence of up to 80% in premenopausal women, and can cause heavy …

Assessing the hepatic safety of epigallocatechin gallate (EGCG) in reproductive-aged women

H Siblini, A Al-Hendy, J Segars, F González, HS Taylor… - Nutrients, 2023 - mdpi.com
A similar abstract of the interim analysis was previously published in Fertility and Sterility.
EPIGALLOCATECHIN GALLATE (EGCG) FOR TREATMENT OF UNEXPLAINED …

The role of tumor necrosis factor α in the biology of uterine fibroids and the related symptoms

M Ciebiera, M Włodarczyk, M Zgliczyńska… - International journal of …, 2018 - mdpi.com
Uterine fibroids (UFs) are the most common benign tumors of the female genital tract. The
incidence of UFs has been estimated at 25–80% depending on selected population. The …

The evolving role of natural compounds in the medical treatment of uterine fibroids

M Ciebiera, M Ali, L Prince, T Jackson-Bey… - Journal of Clinical …, 2020 - mdpi.com
Uterine fibroids (UFs) remain a significant health issue for many women, with a
disproportionate impact on women of color, likely due to both genetic and environmental …

Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment

M Ali, SM Shahin, NA Sabri, A Al-Hendy… - Acta Pharmacologica …, 2019 - nature.com
Uterine fibroids (UFs) are the most common benign neoplastic threat to women's health and
associated with DNA damage and genomic instability. Hypovitaminosis D is a known risk …

Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women

M Ali, S AR, A Al Hendy - Expert review of clinical pharmacology, 2021 - Taylor & Francis
ABSTRACT Introduction Uterine fibroids (UFs) are the most common benign tumor arising
from myometrium of reproductive age women, with significant financial burden estimated in …

Predictive model for drug-induced liver injury using deep neural networks based on substructure space

MG Kang, NS Kang - Molecules, 2021 - mdpi.com
Drug-induced liver injury (DILI) is a major concern for drug developers, regulators, and
clinicians. However, there is no adequate model system to assess drug-associated DILI risk …

The role of cell proliferation and extracellular matrix accumulation induced by food additive butylated hydroxytoluene in uterine leiomyoma

YF Chiang, HY Chen, M Ali, TM Shieh, YJ Huang… - Nutrients, 2021 - mdpi.com
Leiomyoma is the most common benign uterine tumor in reproductive-age women.
Increasing numbers of studies are focusing on the effects of environmental exposure on the …