Current Landscape of Advanced Imaging Tools for Pathology Diagnostics
TM Abraham, R Levenson - Modern Pathology, 2024 - Elsevier
In order for a pathologist to perform histological examination of a tissue sample, the sample
typically must first undergo formalin fixation and paraffin embedding (FFPE) 1. Formalin …
typically must first undergo formalin fixation and paraffin embedding (FFPE) 1. Formalin …
Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning
Systemic amyloidosis involves the deposition of misfolded proteins in organs/tissues,
leading to progressive organ dysfunction and failure. Congo red is the gold-standard …
leading to progressive organ dysfunction and failure. Congo red is the gold-standard …
Label-free morpho-molecular phenotyping of living cancer cells by combined Raman spectroscopy and phase tomography
Accurate, rapid and non-invasive cancer cell phenotyping is a pressing concern across the
life sciences, as standard immuno-chemical imaging and omics require extended sample …
life sciences, as standard immuno-chemical imaging and omics require extended sample …
Quantitative phase imaging of opaque specimens with flexible endoscopic microscopy
J Wang, W You, Y Jiao, Y Zhu, X Liu, X Jiang… - Optics and Lasers in …, 2024 - Elsevier
The flexible endoscope is a minimally invasive tool in clinical settings. Conventional
modalities record bright field images that are usually low contrast and report qualitative …
modalities record bright field images that are usually low contrast and report qualitative …
From Cell Populations to Molecular Complexes: Multiplexed Multimodal Microscopy to Explore p53-53BP1 Molecular Interaction
Surpassing the diffraction barrier revolutionized modern fluorescence microscopy. However,
intrinsic limitations in statistical sampling, the number of simultaneously analyzable …
intrinsic limitations in statistical sampling, the number of simultaneously analyzable …
Virtual Gram staining of label-free bacteria using darkfield microscopy and deep learning
Gram staining has been one of the most frequently used staining protocols in microbiology
for over a century, utilized across various fields, including diagnostics, food safety, and …
for over a century, utilized across various fields, including diagnostics, food safety, and …
Deep learning-assisted low-cost autofluorescence microscopy for rapid slide-free imaging with virtual histological staining
Slide-free imaging techniques have shown great promise in improving the histological
workflow. For example, computational high-throughput autofluorescence microscopy by …
workflow. For example, computational high-throughput autofluorescence microscopy by …
GAN-based quantitative oblique back-illumination microscopy enables computationally efficient epi-mode refractive index tomography
Quantitative oblique back-illumination microscopy (qOBM) is a novel imaging technology
that enables epi-mode 3D quantitative phase imaging and refractive index (RI) tomography …
that enables epi-mode 3D quantitative phase imaging and refractive index (RI) tomography …
Fast and label-free 3D virtual H&E histology via active modulation-assisted dynamic full-field OCT
Z Yin, B He, Y Ying, S Zhang, P Yang, Z Chen… - arXiv preprint arXiv …, 2024 - arxiv.org
Pathological features are the gold standard for tumor diagnosis, guiding treatment and
prognosis. However, standard histopathological process is labor-intensive and time …
prognosis. However, standard histopathological process is labor-intensive and time …
Noninvasive time-lapse 3D subcellular analysis of embryo development for machine learning-enabled prediction of blastocyst formation
chungha lee, geon kim, T Shin, S Lee, JY Kim, KH Choi… - bioRxiv, 2024 - biorxiv.org
In developmental biology and in vitro fertilization (IVF), image-based assessment of embryos
is pivotal. Traditional methods in clinical IVF have been constrained to 2D morphokinetic …
is pivotal. Traditional methods in clinical IVF have been constrained to 2D morphokinetic …