Ageing is the primary risk factor for most neurodegenerative diseases, including Alzheimer
disease (AD) and Parkinson disease (PD). One in ten individuals aged≥ 65 years has AD …

Aging is a major cause of many degenerative diseases. The most intuitive consequence of
aging is mainly manifested on the skin, resulting in cumulative changes in skin structure …

Cellular theory of aging states that human aging is the result of cellular aging, in which an
increasing proportion of cells reach senescence. Senescence, from the Latin word senex …

Due to its ability to cross the epidermis and reach the upper dermis where it causes
cumulative DNA damage and increased oxidative stress, UVB is considered the most …

Cardiac ageing manifests as a decline in function leading to heart failure. At the cellular
level, ageing entails decreased replicative capacity and dysregulation of cellular processes …

Cellular senescence is a form of proliferative arrest triggered in response to a wide variety of
stimuli and characterized by unique changes in cell morphology and function. Although …

The phytochemical epigallocatechin gallate (EGCG) has been reported to alleviate age-
associated immune disorders and organ dysfunction. However, information regarding the …

The significance of diversity, composition, and functional attributes of the gut microbiota in
shaping human health is well recognized. Studies have shown that gut microbiota is closely …

AT is a prototype genome instability syndrome and a multifaceted disease. AT leads to
neurodegeneration− primarily cerebellar atrophy, immunodeficiency, oculocutaneous …

Aging is a time‐related process of functional deterioration at cellular, tissue, organelle, and
organismal level that ultimately brings life to end. Cellular senescence, a state of permanent …