Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) characterized by destruction of the myelin sheath structure. The loss of myelin leads …

The conventional therapeutic approaches to treat autoimmune diseases through
suppressing the immune system, such as steroidal and non-steroidal anti-inflammatory …

Recent studies suggest that training of innate immune cells such as tissue-resident
macrophages by repeated noxious stimuli can heighten host defense responses. However …

The prevalence of immune-mediated disorders, including autoimmune conditions and
allergies, is steadily increasing. However, current therapeutic approaches are often non …

Objectives This study investigated whether exosomes from LPS pretreated bone marrow
mesenchymal stem cells (LPS pre-MSCs) could prolong skin graft survival. Methods The …

Autoimmune diseases are caused by the dysfunction of the body's immune regulatory
system, which leads to the recognition of self-antigens and the destruction of self-tissues and …

Autoimmune diseases, allergies, transplant rejections, generation of antidrug antibodies,
and chronic inflammatory diseases have impacted a large group of people across the globe …

The Helios protein (encoded by the IKZF2 gene) is a member of the Ikaros transcription
family and it has recently been proposed as a promising biomarker for systemic lupus …

Background Mesenchymal stem/stromal cells (MSCs) are multipotent cells with strong tissue
repair and immunomodulatory properties. Due to their ability to repress pathogenic immune …

Background Although kidney transplantation improves patient survival and quality of life,
long-term results are hampered by both immune-and non-immune-mediated complications …