MicroRNAs play important roles in regulating the gene expression and life cycle of cancer
cells. In particular, miR-21, an oncogenic miRNA is a major player involved in tumor …

Neurodegenerative diseases originate from neuronal loss in the central nervous system
(CNS). These debilitating diseases progress with age and have become common due to an …

Introduction The regulatory role of microRNA (miRNA) in several conditions has been
studied, but their function in tendon healing remains elusive. This review summarizes how …

Bone transplantation is one of the most widely performed clinical procedures. Consequently,
bone regeneration using mesenchymal stem cells and tissue engineering strategies is one …

Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterized
by difficulties in social interaction, language development delays, repeated body …

Circulating microRNAs (c-microRNAs, c-miRNAs), which are present in almost all biological
fluids, are promising sensitive biomarkers for various diseases (oncological and …

Medical science has recently advanced to the point where diagnosis and therapeutics can
be carried out with high precision, even at the molecular level. A new field of “precision …

MicroRNAs (miRNAs) have emerged as potential anticancer agents, but their clinical
application is limited by the lack of an effective delivery system to tumors. Exosomes are …

Folate (FA) receptor is a cell surface glycoprotein overexpressed on many cancer cells. It is
a high affinity ligand for cancer cell targeting. However, delivery of siRNA directly through …

With the first RNA interference (RNAi) drug (ONPATTRO (patisiran)) on the market, we
witness the RNAi therapy field reaching a critical turning point, when further improvements in …