[HTML][HTML] Emerging roles of microRNAs in ischemic stroke: as possible therapeutic agents

SE Khoshnam, W Winlow, Y Farbood… - Journal of …, 2017 - ncbi.nlm.nih.gov
Stroke is one of the leading causes of death and physical disability worldwide. The
consequences of stroke injuries are profound and persistent, causing in considerable …

[HTML][HTML] Drug and cell delivery for cardiac regeneration

CL Hastings, ET Roche, E Ruiz-Hernandez… - Advanced drug delivery …, 2015 - Elsevier
The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …

Tissue engineering strategies for the induction of angiogenesis using biomaterials

S Saberianpour, M Heidarzadeh… - Journal of biological …, 2018 - Springer
Angiogenesis is touted as a fundamental procedure in the regeneration and restoration of
different tissues. The induction of de novo blood vessels seems to be vital to yield a …

Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors

H Wang, Y Jiang, H Peng, Y Chen, P Zhu… - Advanced drug delivery …, 2015 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Because
of significant changes in their expression in cancer, miRNAs are believed to be key factors in …

Current status of microRNA-based therapeutic approaches in neurodegenerative disorders

S Paul, LA Bravo Vázquez, S Pérez Uribe… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) are a key gene regulator and play essential roles in several biological
and pathological mechanisms in the human system. In recent years, plenty of miRNAs have …

Current understandings and clinical translation of nanomedicines for breast cancer therapy

Y Jiang, Z Jiang, M Wang, L Ma - Advanced drug delivery reviews, 2022 - Elsevier
Breast cancer is one of the most frequently diagnosed cancers that is threatening women's
life. Current clinical treatment regimens for breast cancer often involve neoadjuvant and …

The interplay among miRNAs, major cytokines, and cancer-related inflammation

C Chakraborty, AR Sharma, G Sharma… - Molecular Therapy-Nucleic …, 2020 - cell.com
Inflammation is closely related with the progression of cancer and is an indispensable
component that orchestrates the tumor microenvironment. Studies suggest that different …

Lantern-shaped flexible RNA origami for Smad4 mRNA delivery and growth suppression of colorectal cancer

M Hu, C Feng, Q Yuan, C Liu, B Ge, F Sun… - Nature …, 2023 - nature.com
Abstract mRNA delivery has shown high application value in the treatment of various
diseases, but its effective delivery is still a major challenge at present. Herein, we propose a …

Plant-derived edible nanoparticles and miRNAs: emerging frontier for therapeutics and targeted drug-delivery

S Iravani, RS Varma - ACS Sustainable Chemistry & Engineering, 2019 - ACS Publications
Rigorous and timely studies have been conducted to develop natural and green
nanomedicines wherein plant-derived edible nanoparticles (PDENs) have a great potential …

Roles of exosomes in the normal and diseased eye

M Klingeborn, WM Dismuke, CB Rickman… - Progress in retinal and …, 2017 - Elsevier
Exosomes are nanometer-sized vesicles that are released by cells in a controlled fashion
and mediate a plethora of extra-and intercellular activities. Some key functions of exosomes …