[HTML][HTML] E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis

S Ma, XY Tian, Y Zhang, C Mu, H Shen, J Bismuth… - Scientific reports, 2016 - nature.com
E-selectin is a surface marker of endothelial cell (EC) inflammation, one of the hallmarks of
atherogenesis. Thus, we tested the hypothesis that delivery of microRNA (miR)-146a and …

[HTML][HTML] Recent insights into the microRNA-dependent modulation of gliomas from pathogenesis to diagnosis and treatment

A Mafi, A Rahmati, Z Babaei Aghdam, R Salami… - Cellular & Molecular …, 2022 - Springer
Gliomas are the most lethal primary brain tumors in adults. These highly invasive tumors
have poor 5-year survival for patients. Gliomas are principally characterized by rapid …

[HTML][HTML] miRNA delivery by nanosystems: state of the art and perspectives

FC Moraes, C Pichon, D Letourneur, F Chaubet - Pharmaceutics, 2021 - mdpi.com
MicroRNAs (miRNAs) are short (~ 21–23 nucleotides), non-coding endogenous RNA
molecules that modulate gene expression at the post-transcriptional level via the …

Hyaluronic acid-coated PEI-PLGA nanoparticles mediated co-delivery of doxorubicin and miR-542-3p for triple negative breast cancer therapy

S Wang, J Zhang, Y Wang, M Chen - … : Nanotechnology, Biology and …, 2016 - Elsevier
MicroRNAs (miRNAs) play critical roles in modulating the oncogenic driver pathways
involved in the acquisition of resistance to cancer treatments. MiR-542-3p serves as a potent …

[HTML][HTML] The role of hypoxia-induced miR-210 in cancer progression

K Dang, KA Myers - International journal of molecular sciences, 2015 - mdpi.com
Prolonged hypoxia, the event of insufficient oxygen, is known to upregulate tumor
development and growth by promoting the formation of a neoplastic environment. The recent …

[HTML][HTML] Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment

Z Liu, M Xiong, J Gong, Y Zhang, N Bai, Y Luo… - Nature …, 2014 - nature.com
Specific targeting and cellular internalization are key properties for carriers of antitumor
therapeutic agents. Here, we develop a drug carrier through the attachment of substrate of …

MiR-146a/b: a family with shared seeds and different roots

MR Paterson, AJ Kriegel - Physiological genomics, 2017 - journals.physiology.org
MicroRNAs are small, noncoding, RNAs known for their powerful modulation of molecular
processes, making them a major focus for studying pathological mechanisms. The human …

Targeted therapeutic delivery using engineered exosomes and its applications in cardiovascular diseases

D Xitong, Z Xiaorong - Gene, 2016 - Elsevier
Exosomes are 30–120 nm membrane bound vesicles secreted naturally by almost all cells
and exist in all body fluids. Accumulating evidence has shown that exosomes contain …

[HTML][HTML] Xeno-nucleic acid (XNA) 2'-fluoro-arabino nucleic acid (FANA) aptamers to the receptor-binding domain of SARS-CoV-2 S protein block ACE2 binding

I Alves Ferreira-Bravo, JJ DeStefano - Viruses, 2021 - mdpi.com
The causative agent of COVID-19, SARS-CoV-2, gains access to cells through interactions
of the receptor-binding domain (RBD) on the viral S protein with angiotensin-converting …

Recent progress in the manipulation of biochemical and biophysical cues for engineering functional tissues

B Bakhshandeh, N Ranjbar, A Abbasi… - Bioengineering & …, 2023 - Wiley Online Library
Tissue engineering (TE) is currently considered a cutting‐edge discipline that offers the
potential for developing treatments for health conditions that negatively affect the quality of …