Lipoprotein-based drug delivery
Lipoproteins (LPs) are circulating heterogeneous nanoparticles produced by the liver and
intestines. LPs play a major role in the transport of dietary and endogenous lipids to target …
intestines. LPs play a major role in the transport of dietary and endogenous lipids to target …
Polymeric nanoparticle mediated inhibition of miR-21 with enhanced miR-124 expression for combinatorial glioblastoma therapy
Glioblastoma (GBM) is the most common and fatal form of malignant brain tumor. Despite
intensive effort, there is still no effective GBM treatment. Therefore, novel and more effective …
intensive effort, there is still no effective GBM treatment. Therefore, novel and more effective …
Nanocarriers for microRNA delivery in cancer medicine
I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
The number of deaths caused by cancer is expected to increase partly due to the lack of
selectivity and undesirable systemic effects of current treatments. Advances in the …
selectivity and undesirable systemic effects of current treatments. Advances in the …
Extracellular miRNAs as mediators of obesity‐associated disease
Extracellular miRNAs are found in a variety of body fluids and mediate intercellular and
interorgan communication, thus regulating gene expression and cellular metabolism. These …
interorgan communication, thus regulating gene expression and cellular metabolism. These …
Regulation of adipogenesis by exosomal milk miRNA
Milk is a rich source of miRNA packaged in exosomes. Evidence for the systemic uptake and
tissue distribution of milk exosomes was reported in newborn and adult humans and …
tissue distribution of milk exosomes was reported in newborn and adult humans and …
Role of noncoding RNAs in the pathogenesis of abdominal aortic aneurysm: possible therapeutic targets?
Abdominal aortic aneurysm (AAA) is a local dilatation of the abdominal aortic vessel wall
and is among the most challenging cardiovascular diseases as without urgent surgical …
and is among the most challenging cardiovascular diseases as without urgent surgical …
Folic‐acid‐mediated functionalized gold nanocages for targeted delivery of anti‐miR‐181b in combination of gene therapy and photothermal therapy against …
S Huang, S Duan, J Wang, S Bao, X Qiu… - Advanced Functional …, 2016 - Wiley Online Library
Therapeutic strategies based on modulation of microRNAs (miRNAs) activity hold much
promise for cancer therapy, but for clinical applications, the efficient delivery of miRNAs to …
promise for cancer therapy, but for clinical applications, the efficient delivery of miRNAs to …
Designing electrospun fiber platforms for efficient delivery of genetic material and genome editing tools
Electrospun fibers are versatile biomaterial platforms with great potential to support
regeneration. Electrospun fiber characteristics such as fiber diameter, degree of alignment …
regeneration. Electrospun fiber characteristics such as fiber diameter, degree of alignment …
Exosomes: Nanoparticulate tools for RNA interference and drug delivery
Exosomes are naturally occurring extracellular vesicles released by most mammalian cells
in all body fluids. Exosomes are known as key mediators in cell‐cell communication and …
in all body fluids. Exosomes are known as key mediators in cell‐cell communication and …
The emerging role of miRNAs in inflammatory bowel disease: a review
CG Chapman, J Pekow - Therapeutic advances in …, 2015 - journals.sagepub.com
Inflammatory bowel disease (IBD), comprised of ulcerative colitis and Crohn's disease, is
believed to develop as a result of a deregulated inflammatory response to environmental …
believed to develop as a result of a deregulated inflammatory response to environmental …