Placental impact of dietary supplements: more than micronutrients

A Rasool, F Alvarado-Flores, P O'Tierney-Ginn - Clinical therapeutics, 2021 - Elsevier
Purpose Maternal nutrition is a key modifier of fetal growth and development. However,
many maternal diets in the United States do not meet nutritional recommendations. Dietary …

Advances in free fatty acid profiles in gestational diabetes mellitus

H Du, D Li, LM Molive, N Wu - Journal of Translational Medicine, 2024 - Springer
The morbidity of gestational diabetes mellitus (GDM) is increasing and is associated with
adverse perinatal outcomes and long-term maternal and infant health. The exact mechanism …

Decreased maternal serum adiponectin and increased insulin-like growth factor-1 levels along with increased placental glucose transporter-1 expression in …

M Balachandiran, Z Bobby, G Dorairajan, V Gladwin… - Placenta, 2021 - Elsevier
Introduction The placental glucose transporter–1 (GLUT-1) is involved in the transplacental
glucose transport to the fetus. GLUT-1 expressions are increased in diabetic pregnancies …

Placental lipid transport and content in response to maternal overweight and gestational diabetes mellitus in human term placenta

L Song, N Wang, Y Peng, B Sun, W Cui - Nutrition, Metabolism and …, 2022 - Elsevier
Background and aims Placental lipid transport is altered in women with high prepregnancy
body mass index (pre-BMI) or gestational diabetes (GDM), which consequently affects foetal …

[HTML][HTML] Maternal high-fat diet impairs placental fatty acid β-oxidation and metabolic homeostasis in the offspring

L Zhang, Z Wang, H Wu, Y Gao, J Zheng… - Frontiers in Nutrition, 2022 - frontiersin.org
Maternal overnutrition can affect fetal growth and development, thus increasing susceptibility
to obesity and diabetes in the offspring. Placenta is the central organ connecting the …

Mechanism of human chorionic gonadotropin in endometrial receptivity via the miR‐126‐3p/PI3K/Akt/eNOS axis

W Wang, L Ge, LL Zhang, LR Wang… - … Journal of Medical …, 2023 - Wiley Online Library
Human chorionic gonadotropin (hCG) might affect endometrial receptivity, exerting integral
roles in embryo implantation. This study explored the action of hCG in endometrial …

[HTML][HTML] Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction

Y Zhang, J Liang, H Gu, T Du, P Xu, T Yu, Q He… - Ecotoxicology and …, 2023 - Elsevier
Ethylhexyl diphenyl phosphate (EHDPP) is one of the typical organophosphate flame
retardants (OPFRs) and has been widely detected in environmental media. Exposure to …

Peroxisome proliferator-activated receptors and placental function in women with polycystic ovary syndrome

A Silva, A Motta - Reproduction, 2024 - rep.bioscientifica.com
In brief Adverse pregnancy outcomes in women with polycystic ovary syndrome (PCOS) are
frequently associated with abnormal placental functions. This review explores the …

Early-life exposure to gestational diabetes mellitus predisposes offspring to pediatric nonalcoholic fatty liver disease

QR Zhang, Y Dong, JG Fan - Hepatobiliary & Pancreatic Diseases …, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as the prevailing chronic liver
disease in the pediatric population due to the global obesity pandemic. Evidence shows that …

Expression of placental lipid transporters in pregnancies complicated by gestational and type 1 diabetes mellitus

PJ Stanirowski, M Wątroba, M Pyzlak… - International Journal of …, 2024 - mdpi.com
The objective of the study was to assess the expression of proteins responsible for placental
lipid transport in term pregnancies complicated by well-controlled gestational (GDM) and …