Engineering of BODIPY-based theranostics for cancer therapy

Z Mao, JH Kim, J Lee, H Xiong, F Zhang… - Coordination Chemistry …, 2023 - Elsevier
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …

Biological action of singlet molecular oxygen from the standpoint of cell signaling, injury and death

J Fujii, Y Soma, Y Matsuda - Molecules, 2023 - mdpi.com
Energy transfer to ground state triplet molecular oxygen results in the generation of singlet
molecular oxygen (1O2), which has potent oxidizing ability. Irradiation of light, notably …

Enzyme-responsive double-locked photodynamic molecular beacon for targeted photodynamic anticancer therapy

LKB Tam, JCH Chu, L He, C Yang… - Journal of the …, 2023 - ACS Publications
An advanced photodynamic molecular beacon (PMB) was designed and synthesized, in
which a distyryl boron dipyrromethene (DSBDP)-based photosensitizer and a Black Hole …

Trial watch: chemotherapy-induced immunogenic cell death in oncology

J Sprooten, RS Laureano, I Vanmeerbeek… - …, 2023 - Taylor & Francis
Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell
death that activates, rather than suppresses, innate and adaptive immune responses. Such …

Different types of cell death and their shift in shaping disease

S Shen, Y Shao, C Li - Cell death discovery, 2023 - nature.com
Cell death is the irreversible stop of life. It is also the basic physiological process of all
organisms which involved in the embryonic development, organ maintenance and …

Paraptosis: A unique cell death mode for targeting cancer

S Hanson, A Dharan, J PV, S Pal, BG Nair… - Frontiers in …, 2023 - frontiersin.org
Programmed cell death (PCD) is the universal process that maintains cellular homeostasis
and regulates all living systems' development, health and disease. Out of all, apoptosis is …

A near-infrared light-activatable Ru (ii)-coumarin photosensitizer active under hypoxic conditions

E Ortega-Forte, A Rovira, M López-Corrales… - Chemical …, 2023 - pubs.rsc.org
Photodynamic therapy (PDT) represents a promising approach for cancer treatment.
However, the oxygen dependency of PDT to generate reactive oxygen species (ROS) …

The Photosensitizer Temoporfin (mTHPC) – Chemical, Pre‐clinical and Clinical Developments in the Last Decade

A Wiehe, MO Senge - Photochemistry and Photobiology, 2023 - Wiley Online Library
This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …

Shining a light on prostate cancer: photodynamic therapy and combination approaches

H Wahnou, I Youlyouz-Marfak, B Liagre, V Sol… - Pharmaceutics, 2023 - mdpi.com
Prostate cancer is a major health concern worldwide, and current treatments, such as
surgery, radiation therapy, and chemotherapy, are associated with significant side effects …

[HTML][HTML] Ferroptosis-mediated immune responses in cancer

D Qi, M Peng - Frontiers in Immunology, 2023 - frontiersin.org
Cell death is a universal biological process in almost every physiological and pathological
condition, including development, degeneration, inflammation, and cancer. In addition to …