Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …

Post-transcriptional gene regulation (PTGR) concerns processes involved in the maturation,
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …

Abstract Although 5-methylcytosine (m5C) is a widespread modification in RNAs, its
regulation and biological role in pathological conditions (such as cancer) remain unknown …

The dynamic and reversible N 6-methyladenosine (m 6 A) RNA modification installed and
erased by N 6-methyltransferases and demethylases regulates gene expression and cell …

HuR influences gene expression programs and hence cellular phenotypes by binding to
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …

Long non-coding RNAs (lncRNAs) are emerging regulators of pathophysiological processes
including atherosclerosis. Using RNA-seq profiling of the intima of lesions, here we identify a …

Abstract N 6-methyladenosine (m6A) is the most prevalent internal (non-cap) modification
present in the messenger RNA of all higher eukaryotes,. Although essential to cell viability …

Cellular RNAs carry diverse chemical modifications that used to be regarded as static and
having minor roles in'fine-tuning'structural and functional properties of RNAs. In this Review …

Abstract The methyltransferase like 3 (METTL3)-containing methyltransferase complex
catalyzes the N6-methyladenosine (m6A) formation, a novel epitranscriptomic marker; …

Sequence-specific RNA-binding proteins (RBPs) bind to pre-mRNA to control alternative
splicing, but it is not yet possible to read the'splicing code'that dictates splicing regulation on …