Effect of pentoxifylline on radiation-induced lung and skin toxicity in rats

WJ Koh, KJ Stelzer, LM Peterson, BL Staker… - International Journal of …, 1995 - Elsevier
Purpose: There is currently substantial clinical interest in pentoxifylline as an inhibitor of
radiation-related normal tissue injury. To further assess this drug's potential toxicity-sparing …

Analysis of single nucleotide polymorphisms and radiation sensitivity of the lung assessed with an objective radiologic endpoin

CR Kelsey, IL Jackson, S Langdon, K Owzar, J Hubbs… - Clinical lung cancer, 2013 - Elsevier
Background The primary objective of this study was to evaluate the association between
radiation sensitivity of the lungs and candidate single nucleotide polymorphisms (SNP) in …

An image acquisition and registration strategy for the fusion of hyperpolarized helium-3 MRI and x-ray CT images of the lung

RH Ireland, N Woodhouse, N Hoggard… - Physics in Medicine …, 2008 - iopscience.iop.org
The purpose of this ethics committee approved prospective study was to evaluate an image
acquisition and registration protocol for hyperpolarized helium-3 magnetic resonance …

[HTML][HTML] Lung perfusion imaging can risk stratify lung cancer patients for the development of pulmonary complications after chemoradiation

IW Gayed, J Chang, EE Kim, R Nuñez… - Journal of Thoracic …, 2008 - Elsevier
Introduction We investigated the value of lung perfusion imaging in predicting the risk of
developing pulmonary complications after chemoradiation (CRT) or radiation therapy (RT) …

Circulating thrombomodulin during radiation therapy of lung cancer

M Hauer‐Jensen, FM Kong, LM Fink… - … : Clinical and Basic …, 1999 - Wiley Online Library
The endothelial cell glycoprotein, thrombomodulin (TM), is an important physiological
anticoagulant. TM is downregulated and released from the cell membrane into the …

The prediction of radiation‐induced liver dysfunction using a local dose and regional venous perfusion model

Y Cao, JF Platt, IR Francis, JM Balter, C Pan… - Medical …, 2007 - Wiley Online Library
We have shown that high dose conformal radiation combined with chemotherapy appears to
prolong the survival of patients with unresectable intrahepatic cancers. The ability to safely …

The role of nuclear medicine in the prediction and detection of radiation-associated normal pulmonary and cardiac damage

I Goethals, R Dierckx, G De Meerleer… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Dose–effect calculations used in the planning of modern radiotherapy (RT) involving normal
lung or cardiac tissue rely on structural imaging techniques, such as CT, as the basis for …

Characterizing spatial differences between SPECT-ventilation and SPECT-perfusion in patients with lung cancer undergoing radiotherapy

F Forghani, T Patton, J Kwak, D Thomas, Q Diot… - Radiotherapy and …, 2021 - Elsevier
This study investigates agreement between ventilation and perfusion for lung cancer
patients undergoing radiotherapy. Ventilation-perfusion scans of nineteen patients with …

Recovery of overall and local lung function loss 18 months after irradiation for malignant lymphoma.

LJ Boersma, EM Damen, RW de Boer… - Journal of clinical …, 1996 - ascopubs.org
PURPOSE To determine the local and overall pulmonary injury 3 to 18 months after
irradiation and to investigate whether the changes in overall lung function can be predicted …

Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor (M6P/IGF2R) locus predisposes patients to radiation-induced lung injury

FM Kong, MS Anscher, TA Sporn… - International Journal of …, 2001 - Elsevier
Purpose: To investigate the relationship between loss of heterozygosity (LOH) at the
mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) gene locus and the …