The role of cullin 5-containing ubiquitin ligases

F Okumura, A Joo-Okumura, K Nakatsukasa, T Kamura - Cell division, 2016 - Springer
The suppressor of cytokine signaling (SOCS) box consists of the BC box and the cullin 5
(Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing …

[HTML][HTML] Vascularized polypeptide hydrogel modulates macrophage polarization for wound healing

Z Chen, L Wang, C Guo, M Qiu, L Cheng, K Chen, J Qi… - Acta Biomaterialia, 2023 - Elsevier
Wound repair involves a sophisticated process that includes angiogenesis,
immunoregulation and collagen deposition. However, weak revascularization performance …

[HTML][HTML] The functions and properties of cullin-5, a potential therapeutic target for cancers

F Gao, Y Fan, B Zhou, W Guo, X Jiang… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Cullin-5 (CUL5), a scaffold protein in active cullin-RING ubiquitin ligase (CRL)
complexes, is a member of the cullin family of proteins. The CUL5-type ubiquitin ligase can …

Cullin-5, a ubiquitin ligase scaffold protein, is significantly underexpressed in endometrial adenocarcinomas and is a target of miR-182

EJ Devor, BM Schickling, HD Reyes… - Oncology …, 2016 - spandidos-publications.com
Altered expression of cullin-5 (CUL5), a member of the cullin-RING E3 ubiquitin ligase
family, has been implicated in a number of types of cancers including breast, cervical and …

[HTML][HTML] Culin5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF

L Wang, J Huang, R Zhang, M Zhang, Y Guo, Y Liu… - Iscience, 2023 - cell.com
Hypoxic pulmonary hypertension (HPH) lacks effective pharmacologic treatments.
Microarray-based gene expression indicates the crucial role of Cullin 5 (Cul 5) in HPH. This …

[PDF][PDF] Vasopressin in preeclampsia

JA Sandgren - 2019 - iro.uiowa.edu
Preeclampsia is a devastating disorder of pregnancy characterized by high blood pressure,
proteinuria, headache, renal glomerular endotheliosis, multi-organ system failure, and fetal …

The molecular interaction of feline immunodeficiency virus Vif with feline APOBEC3 and Cullin 5

Q Gu - 2018 - jlupub.ub.uni-giessen.de
The apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like (APOBEC3, A3)
family of DNA cytidine deaminases are intrinsic restriction factors against retroviruses. In …