Recent advances in targeted drug delivery strategy for enhancing oncotherapy

J Li, Q Wang, G Xia, N Adilijiang, Y Li, Z Hou, Z Fan… - Pharmaceutics, 2023 - mdpi.com
Targeted drug delivery is a precise and effective strategy in oncotherapy that can accurately
deliver drugs to tumor cells or tissues to enhance their therapeutic effect and, meanwhile …

Application of nanoparticles in cancer treatment: a concise review

M Sell, AR Lopes, M Escudeiro, B Esteves… - Nanomaterials, 2023 - mdpi.com
Timely diagnosis and appropriate antitumoral treatments remain of utmost importance, since
cancer remains a leading cause of death worldwide. Within this context, nanotechnology …

Nanoparticle-mediated hyperthermia and cytotoxicity mechanisms in cancer

VM Bala, DI Lampropoulou, S Grammatikaki… - International Journal of …, 2023 - mdpi.com
Hyperthermia has the potential to damage cancerous tissue by increasing the body
temperature. However, targeting cancer cells whilst protecting the surrounding tissues is …

Empagliflozin: a potential anticancer drug

W Wu, Y Wang, J Xie, S Fan - Discover Oncology, 2023 - Springer
Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, is a highly effective and
well-tolerated antidiabetic drug. In addition to hypoglycemic effects, empagliflozin has many …

[HTML][HTML] Catalase-gold nanoaggregates manipulate the tumor microenvironment and enhance the effect of low-dose radiation therapy by reducing hypoxia

A Najafi, M Keykhaee, MH Kazemi, MY Karimi… - Biomedicine & …, 2023 - Elsevier
Radiotherapy as a standard method for cancer treatment faces tumor recurrence and
antitumoral unresponsiveness. Suppressive tumor microenvironment (TME) and hypoxia are …

Nonpersistent Nanoarchitectures Enhance Concurrent Chemoradiotherapy in an Immunocompetent Orthotopic Model of HPV+ Head/Neck Carcinoma

A Gonnelli, M Gerbé de Thoré, ML Ermini… - Advanced …, 2024 - Wiley Online Library
Cisplatin chemoradiotherapy (CRT) is the established standard of care for managing locally
advanced human papillomavirus‐positive head/neck carcinoma. The typically young …

Inorganic nanoparticles as radiosensitizers for cancer treatment

B Babu, SA Stoltz, A Mittal, S Pawar, E Kolanthai… - Nanomaterials, 2023 - mdpi.com
Nanotechnology has expanded what can be achieved in our approach to cancer treatment.
The ability to produce and engineer functional nanoparticle formulations to elicit higher …

Peptide-Hitchhiking for the Development of Nanosystems in Glioblastoma

F Branco, J Cunha, M Mendes, C Vitorino, JJ Sousa - ACS nano, 2024 - ACS Publications
Glioblastoma (GBM) remains the epitome of aggressiveness and lethality in the spectrum of
brain tumors, primarily due to the blood–brain barrier (BBB) that hinders effective treatment …

Selenium‐Doped Nanoheterojunctions for Highly Efficient Cancer Radiosensitization

R Qiao, Z Yuan, M Yang, Z Tang, L He… - Advanced …, 2024 - Wiley Online Library
Exploring efficient and low‐toxicity radiosensitizers to break through the bottleneck of
radiation tolerance, immunosuppression and poor prognosis remains one of the critical …

Toward the scale-up production of polymeric nanotherapeutics for cancer clinical trials

MM Mahmud, N Pandey, JA Winkles, GF Woodworth… - Nano Today, 2024 - Elsevier
Nanotherapeutics have gained significant attention for the treatment of numerous cancers,
primarily because they can accumulate in and/or selectively target tumors leading to …