The cardiovascular complications contribute to a majority of diabetes associated morbidity
and mortality, accounting for 44% of death in those patients with type 1 diabetes mellitus …

The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …

The vascular endothelial growth factor (VEGF) family, the crucial regulator of angiogenesis,
lymphangiogenesis, lipid metabolism and inflammation, is involved in the development of …

The lymphatic vasculature has an essential role in maintaining normal fluid balance in
tissues and modulating the inflammatory response to injury or pathogens. Disruption of …

In recent decades, treatments for myocardial infarction (MI), such as stem and progenitor cell
therapy, have attracted considerable scientific and clinical attention but failed to improve …

The lymphatic vasculature has a pivotal role in regulating body fluid homeostasis, immune
surveillance and dietary fat absorption. The increasing number of in vitro and in vivo studies …

Ischemic cardiomyopathy (ICM) is the leading cause of heart failure worldwide, yet the
cellular and molecular signature of this disease is largely unclear. Using single-nucleus …

Macrophages were first described as phagocytic immune cells responsible for maintaining
tissue homeostasis by the removal of pathogens that disturb normal function. Historically …

Lymphatic vessels are low-pressure, blind-ended tubular structures that play a crucial role in
the maintenance of tissue fluid homeostasis, immune cell trafficking, and dietary lipid uptake …

Infection by the protozoan Trypanosoma cruzi causes Chagas disease cardiomyopathy
(CCC) and can lead to arrhythmia, heart failure and death. Chagas disease affects 8 million …