The function of the mammalian heart depends on the interplay between different cardiac cell
types. The deployment of these cells, with precise spatiotemporal regulation, is also …

A complex interaction exists between the nervous and cardiovascular systems. A large
network of cortical and subcortical brain regions control cardiovascular function via the …

The cardiac autonomic nervous system (CANS) plays a key role for the regulation of cardiac
activity with its dysregulation being involved in various heart diseases, such as cardiac …

OBJECTIVE Impaired glucose tolerance (IGT) represents one of the earliest stages of
glucose dysregulation and is associated with macrovascular disease, retinopathy, and …

Differentiated derivatives of human pluripotent stem cells (hPSCs) are often considered
immature because they resemble foetal cells more than adult, with hPSC-derived …

Autonomic cardiac neurons have a common origin in the neural crest but undergo distinct
developmental differentiation as they mature toward their adult phenotype. Progenitor cells …

Aims The long-QT syndrome (LQTS) represents a leading cause of sudden cardiac death
(SCD). The aim of this study was to assess the presence of an underlying electroanatomical …

The autonomic nervous system (ANS) is complex and plays an important role in cardiac
arrhythmia pathogenesis. A deeper understanding of the anatomy and development of the …

Neurotrophins (NTs) were first identified as target-derived survival factors for neurons of the
central and peripheral nervous system (PNS). They are known to control neural cell fate …

Neurons derived from human pluripotent stem cells (hPSCs) are powerful tools for studying
human neural development and diseases. Robust functional coupling of hPSC-derived …