Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
Antigenic Variation in Plasmodium falciparum
The persistence of the human malaria parasite Plasmodium falciparum during blood stage
proliferation in its host depends on the successive expression of variant molecules at the …
proliferation in its host depends on the successive expression of variant molecules at the …
Plasmodium falciparum Erythrocyte Membrane Protein 1 Diversity in Seven Genomes – Divide and Conquer
TS Rask, DA Hansen, TG Theander… - PLoS computational …, 2010 - journals.plos.org
The var gene encoded hyper-variable Plasmodium falciparum erythrocyte membrane
protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human …
protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human …
[HTML][HTML] Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes
A major part of virulence for Plasmodium falciparum malaria infection, the most lethal
parasitic disease of humans, results from increased rigidity and adhesiveness of infected …
parasitic disease of humans, results from increased rigidity and adhesiveness of infected …
Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children
T Lavstsen, L Turner, F Saguti… - Proceedings of the …, 2012 - National Acad Sciences
The clinical outcome of Plasmodium falciparum infections ranges from asymptomatic
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …
Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Malaria in pregnancy: from placental infection to its abnormal development and damage
CLL Chua, SKM Khoo, JLE Ong… - Frontiers in …, 2021 - frontiersin.org
Malaria remains a global health burden with Plasmodium falciparum accounting for the
highest mortality and morbidity. Malaria in pregnancy can lead to the development of …
highest mortality and morbidity. Malaria in pregnancy can lead to the development of …
Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
MD Larsen, M Lopez-Perez, EK Dickson… - Nature …, 2021 - nature.com
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
[HTML][HTML] Malaria in pregnancy: linking immunity and pathogenesis to prevention
SJ Rogerson, V Mwapasa… - Defining and Defeating …, 2007 - ncbi.nlm.nih.gov
Pregnant women are susceptible to malaria during pregnancy. Plasmodium falciparum,
which sequesters in the placenta, causes the greatest disease, contributing significantly to …
which sequesters in the placenta, causes the greatest disease, contributing significantly to …
Antigenic Variation in Plasmodium falciparum: Gene Organization and Regulation of the var Multigene Family
SA Kyes, SM Kraemer, JD Smith - Eukaryotic cell, 2007 - Am Soc Microbiol
Plasmodium falciparum imposes an enormous burden upon the developing world, with 300
to 500 million cases and 1 to 2 million deaths per year (94). Despite extensive research …
to 500 million cases and 1 to 2 million deaths per year (94). Despite extensive research …