[HTML][HTML] A review and a framework of variables for defining and characterizing tinnitus subphenotypes

E Genitsaridi, DJ Hoare, T Kypraios, DA Hall - Brain sciences, 2020 - mdpi.com
Tinnitus patients can present with various characteristics, such as those related to the
tinnitus perception, symptom severity, and pattern of comorbidities. It is speculated that this …

[HTML][HTML] Neuroanatomical alterations in middle frontal gyrus and the precuneus related to tinnitus and tinnitus distress

S Rosemann, JP Rauschecker - Hearing Research, 2022 - Elsevier
Tinnitus is the phantom perception of sound when there is no external auditory input. This
sound is mostly perceived as a ringing, whistling or buzzing in the ear. There is evidence of …

[HTML][HTML] Efficacy and safety of AM-101 in the treatment of acute inner ear tinnitus—a double-blind, randomized, placebo-controlled phase II study

P Van de Heyning, G Muehlmeier, T Cox… - Otology & …, 2014 - journals.lww.com
Objective To evaluate the efficacy and safety of intratympanic AM-101 in patients with
persistent acute inner ear tinnitus after acute acoustic trauma, idiopathic sudden …

Pharmacological approaches to the treatment of tinnitus

AB Elgoyhen, B Langguth - Drug discovery today, 2010 - Elsevier
Tinnitus is the conscious perception of a phantom sound in the absence of an external
source. For 1 in 100 of the general population, the condition severely affects quality of life. In …

Comparison of amplitude modulated sounds and pure tones at the tinnitus frequency: residual tinnitus suppression and stimulus evaluation

P Neff, L Zielonka, M Meyer, B Langguth… - Trends in …, 2019 - journals.sagepub.com
Recent studies have compared tinnitus suppression, or residual inhibition, between
amplitude-and frequency-modulated (AM) sounds and noises or pure tones (PT). Results …

[HTML][HTML] Tinnitus patients with comorbid headaches: the influence of headache type and laterality on tinnitus characteristics

B Langguth, V Hund, M Landgrebe… - Frontiers in …, 2017 - frontiersin.org
Background Both clinical experience and clinical studies suggest a relationship between
tinnitus and headache. Here, we aimed to investigate the influence of comorbid headache …

[HTML][HTML] The effect of physical therapy treatment in patients with subjective tinnitus: a systematic review

S Michiels, S Naessens, P Van de Heyning… - Frontiers in …, 2016 - frontiersin.org
Background: Tinnitus is a very common symptom that often causes distress and decreases
the patient's quality of life. Apart from the well-known causes, tinnitus can in some cases be …

[HTML][HTML] A randomized single-blind controlled trial of a prototype digital polytherapeutic for tinnitus

GD Searchfield, PJ Sanders - Frontiers in Neurology, 2022 - frontiersin.org
Objective This randomized single-blind controlled trial tested the hypothesis that a prototype
digital therapeutic developed to provide goal-based counseling with personalized passive …

[HTML][HTML] Insomnia associated with tinnitus and gender differences

K Richter, M Zimni, I Tomova, L Retzer, J Höfig… - International Journal of …, 2021 - mdpi.com
Chronic tinnitus causes a decrease in well-being and can negatively affect sleep quality. It
has further been indicated that there are clinically relevant gender differences, which may …

[HTML][HTML] The effect of antioxidant supplementation in patients with tinnitus and normal hearing or hearing loss: a randomized, double-blind, placebo controlled trial

AI Petridou, ET Zagora, P Petridis, GS Korres… - Nutrients, 2019 - mdpi.com
Tinnitus is the perception of sound in the absence of any external stimulus. Oxidative stress
is possibly involved in its pathogenesis and a variety of antioxidant compounds have been …