Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Methyl donor micronutrients that modify DNA methylation and cancer outcome

AM Mahmoud, MM Ali - Nutrients, 2019 - mdpi.com
DNA methylation is an epigenetic mechanism that is essential for regulating gene
transcription. However, aberrant DNA methylation, which is a nearly universal finding in …

Cancer screening in China: the current status, challenges, and suggestions

M Cao, H Li, D Sun, S He, Y Yu, J Li, H Chen, J Shi… - Cancer Letters, 2021 - Elsevier
Substantial progress has been made in cancer screening in China due to the substantial
efforts of all levels of the government. Four large-scale population-based screening …

The role of cigarette smoke-induced epigenetic alterations in inflammation

D Zong, X Liu, J Li, R Ouyang, P Chen - Epigenetics & Chromatin, 2019 - Springer
Background Exposure to cigarette smoke (CS) is a major threat to human health worldwide.
It is well established that smoking increases the risk of respiratory diseases, cardiovascular …

Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer

P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

Dual methylation-sensitive restriction endonucleases coupling with an RPA-assisted CRISPR/Cas13a system (DESCS) for highly sensitive analysis of DNA …

X Wang, S Zhou, C Chu, M Yang, D Huo, C Hou - ACS sensors, 2021 - ACS Publications
High-performance detection of DNA methylation possesses great significance for the
diagnosis and therapy of cancer. Herein, for the first time, we present a digestion strategy …

Recent advances of nucleic acid-based cancer biomarkers and biosensors

J Zhao, K Xia, P He, G Wei, X Zhou, X Zhang - Coordination Chemistry …, 2023 - Elsevier
Nucleic acid-based cancer biomarkers (NABCBs) have emerged as a notable and
continuously captivating research focal point within the domain of oncology. As a result …

The role of cigarette smoke-induced pulmonary vascular endothelial cell apoptosis in COPD

Q Song, P Chen, XM Liu - Respiratory Research, 2021 - Springer
Chronic obstructive pulmonary disease (COPD) is one of the most common chronic
respiratory diseases with high morbidity and mortality. It has become the fifth most burdened …

Stress and coping in women with breast cancer: unravelling the mechanisms to improve resilience

M Borgi, B Collacchi, E Ortona, F Cirulli - Neuroscience & Biobehavioral …, 2020 - Elsevier
Breast cancer diagnosis, surgery, adjuvant therapies and survivorship can all be extremely
stressful. In women, concerns about body image are common as a result of the disease and …

Epigenetic polypharmacology: A new frontier for epi‐drug discovery

D Tomaselli, A Lucidi, D Rotili… - Medicinal research …, 2020 - Wiley Online Library
Recently, despite the great success achieved by the so‐called “magic bullets” in the
treatment of different diseases through a marked and specific interaction with the target of …