[HTML][HTML] Estimating risk of antidepressant withdrawal from a review of published data
MA Horowitz, A Framer, MP Hengartner, A Sørensen… - CNS drugs, 2023 - Springer
Adaptation of the brain to the presence of a drug predicts withdrawal on cessation. The
outcome of adaptation is often referred to as 'physical dependence'in pharmacology, as …
outcome of adaptation is often referred to as 'physical dependence'in pharmacology, as …
Clozapine discontinuation withdrawal symptoms in schizophrenia
G Blackman, E Oloyede - Therapeutic Advances in …, 2021 - journals.sagepub.com
Clozapine is an atypical antipsychotic used in treatment-resistant schizophrenia. Whilst
clozapine is highly effective, there are some clinical scenarios, such as the emergence of …
clozapine is highly effective, there are some clinical scenarios, such as the emergence of …
A method for tapering antipsychotic treatment that may minimize the risk of relapse
The process of stopping antipsychotics may be causally related to relapse, potentially linked
to neuroadaptations that persist after cessation, including dopaminergic hypersensitivity …
to neuroadaptations that persist after cessation, including dopaminergic hypersensitivity …
Experiences of reduction and discontinuation of antipsychotics: a qualitative investigation within the RADAR trial
Background Antipsychotics are a core treatment for psychosis, but the evidence for gradual
dose reductions guided by clinicians is under-developed. The RADAR randomised …
dose reductions guided by clinicians is under-developed. The RADAR randomised …
The human neurosecretome: Extracellular vesicles and particles (EVPs) of the brain for intercellular communication, therapy, and liquid-biopsy applications
Emerging evidence suggests that brain derived extracellular vesicles (EVs) and particles
(EPs) can cross blood-brain barrier and mediate communication among neurons, astrocytes …
(EPs) can cross blood-brain barrier and mediate communication among neurons, astrocytes …
Management of antipsychotics in primary care: Insights from healthcare professionals and policy makers in the United Kingdom
Introduction Antipsychotic medication is increasingly prescribed to patients with serious
mental illness. Patients with serious mental illness often have cardiovascular and metabolic …
mental illness. Patients with serious mental illness often have cardiovascular and metabolic …
Opinion Piece: The case for establishing a minimal medication alternative for psychosis and schizophrenia
RE Cooper, JP Mason, T Calton, J Richardson… - Psychosis, 2021 - Taylor & Francis
The development of severe mental health conditions is strongly linked to our environments,
particularly experiences of trauma and adversity. However treatments for severe mental …
particularly experiences of trauma and adversity. However treatments for severe mental …
Tapering antipsychotic medication: practical considerations
MA Horowitz, J Moncrieff, L de Haan… - Psychological …, 2022 - cambridge.org
Antipsychotic medications are the gold-standard treatment for psychotic patients, and their
efficacy is evident (Kahn et al., 2018). Most guidelines recommend long-term, continuous …
efficacy is evident (Kahn et al., 2018). Most guidelines recommend long-term, continuous …
[HTML][HTML] The experiences of 585 people when they tried to withdraw from antipsychotic drugs
J Read - Addictive behaviors reports, 2022 - Elsevier
Introduction Many recipients of antipsychotic drugs try to stop taking them, primarily because
of distressing adverse effects. Little research has been undertaken into the withdrawal …
of distressing adverse effects. Little research has been undertaken into the withdrawal …
A scoping review: Treatment attitudes and adherence for adults with schizophrenia
Aim and objectives This scoping review presents an exploration of literature on the
relationship between treatment attitudes and adherence in adults experiencing …
relationship between treatment attitudes and adherence in adults experiencing …