Although issues associated with returning individual research results to study participants
have been well explored, these issues have been less thoroughly investigated in vulnerable …

428 Circ Cardiovasc Genet August 2013 for each specific region of the genome tested. A
typical exome has a median read-depth of 50; each exon shows≈ 50 independent reads. In …

Introduction: Many research programs are challenged to accommodate low-resource
research participants'(LRRP) ancillary care needs when returning genomic research results …

The potential for next generation sequencing research (NGS) to generate individual genetic
results could have implications for the informed consent process and the provision of genetic …

Abstract The use of Whole-Genome Sequencing (WGS) in clinical settings has brought up a
number of controversial scientific and ethical issues. The application of WGS is of particular …

New high‐throughput 'omics techniques are providing exciting opportunities in clinical
medicine and toxicology, especially in the development of biomarkers. In health science …

There is an urgent need for consistent data sharing policies that promote the advancement
of science while respecting the values and interests of those providing their genetic data for …

The use of next generation sequencing (NGS) technologies in psychiatric genetics research
and its potential to generate individual research results will likely have far reaching …

Awareness of ethical issues that may be raised by the implementation of nutrigenetic/
nutrigenomic (NGx) testing and personalized nutrition, at an individual or a public health …

This is an exciting time to work in medicine. The enormous advances in our understanding
of inherited diseases that have flowed from sequencing the human genome mean that many …