Natural alternatives replacing artificial additives have gained much attention in the
consumer's view because of the growing search for clean label products that are devoid of …

Chrysin, a flavonoid, has played a great role in the fields of anticancer, antibacterial, and
antiviral drug discovery. A large number of chrysin derivatives have been synthesized …

Hybrid compounds of flavones, namely chrysin and kaempferol, and substituted 1, 2, 3-
triazole derivatives, were synthesized by click reaction of the intermediate O-propargyl …

Chrysin is a natural flavonoid that despite having numerous biological properties, its
therapeutic value is limited due to its very low solubility in aqueous media. In this work …

Fatty acid biosynthesis is essential for bacterial survival. Of these promising targets, β‐
ketoacyl‐acyl carrier protein (ACP) synthase III (FabH) is the most attractive target. A series …

Hybrid molecules can be defined as chemical entities with two or more structural domains,
namely pharmacophores, having a specific biological effect. In many cases, when at least …

A series sterically‐encumbered coumarin‐(1) and chrysin‐functionalized triazolium salts (2,
3) have been synthesized stepwise via copper catalyzed alkyne–azide cycloaddition and N …

Finding naturally occurring antimicrobial compounds with little danger to human health is
essential since microorganisms are growing more and more resistant to antibiotics. This …

Chrysin is a widely distributed natural flavonoid with broad biological activities, but its poor
bioavailability and insufficient efficacy limit its clinical applications. Based on prodrug and …

过量的处方和抗生素滥用导致了耐药菌株的发展, 而当前处于研发管线中的抗菌药物数量过少,
加大了人们对抗耐药菌药物研发的需求, 同时迫切需要新技术的介入以加快研发进程 …