Bacteria belonging to the genus Streptococcus are the first inhabitants of the oral cavity,
which can be acquired right after birth and thus play an important role in the assembly of the …

Within the past decade, clinical microbiology laboratories experienced revolutionary
changes in the way in which microorganisms are identified, moving away from slow …

Until recently, microbial identification in clinical diagnostic laboratories has mainly relied on
conventional phenotypic and gene sequencing identification techniques. The development …

Dental biofilms produce acids from carbohydrates that result in caries. According to the
extended caries ecological hypothesis, the caries process consists of 3 reversible stages …

Background. Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass
spectrometry accurately identifies both selected bacteria and bacteria in select clinical …

The qualified presumption of safety (QPS) approach was developed to provide a generic pre‐
evaluation of the safety of biological agents. The QPS approach is based on an assessment …

Dental caries in very young children may be severe, result in serious infection, and require
general anesthesia for treatment. Dental caries results from a shift within the biofilm …

More than 700 bacterial species or phylotypes, of which over 50% have not been cultivated,
have been detected in the oral cavity. Our purposes were (i) to utilize culture-independent …

To help advance the species definition for prokaryotes, we have compared the gene content
of 70 closely related and fully sequenced bacterial genomes to identify whether species …

The Human Microbiome Project provided a census of bacterial populations in healthy
individuals, but an understanding of the biomedical significance of this census has been …