Stimulus-responsive drug/gene delivery system based on polyethylenimine cyclodextrin nanoparticles for potential cancer therapy

H Mousazadeh, E Bonabi, N Zarghami - Carbohydrate Polymers, 2022 - Elsevier
Combination therapy through simultaneous delivery of anti-cancer drugs and genes with
nano-assembled structure has been proved to be a simple and effective approach for …

Recent advances in codelivery of curcumin and siRNA as anticancer therapeutics

M Sanati, AR Afshari, P Kesharwani… - European Polymer …, 2023 - Elsevier
Addressing the need for effective cancer chemotherapy with low adverse effects has been
partially possible through innovative therapeutic approaches combining chemotherapeutics …

Imaging biomarkers for clinical applications in neuro-oncology: current status and future perspectives

FY Chiu, Y Yen - Biomarker Research, 2023 - Springer
Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …

Long non-coding RNAs as new players in bladder cancer: Lessons from pre-clinical and clinical studies

S Mirzaei, MDA Paskeh, F Hashemi, A Zabolian… - Life Sciences, 2022 - Elsevier
The clinical management of bladder cancer (BC) has become an increasing challenge due
to high incidence rate of BC, malignant behavior of cancer cells and drug resistance. The …

Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery

Y Hu, Z Dong, K Liu - Journal of Experimental & Clinical Cancer Research, 2024 - Springer
Signal transducer and activator of transcription 3 (STAT3) is a transcriptional factor involved
in almost all cancer hallmark features including tumor proliferation, metastasis …

Nonspherical metal‐based nanoarchitectures: synthesis and impact of size, shape, and composition on their biological activity

EN Zare, X Zheng, P Makvandi, H Gheybi, R Sartorius… - Small, 2021 - Wiley Online Library
Metal‐based nanoentities, apart from being indispensable research tools, have found
extensive use in the industrial and biomedical arena. Because their biological impacts are …

Insights into the involvement of long non-coding RNAs in doxorubicin resistance of cancer

HB Zhang, Y Hu, JL Deng, GY Fang… - Frontiers in …, 2023 - frontiersin.org
Doxorubicin is one of the most classical chemotherapeutic drugs for the treatment of cancer.
However, resistance to the cytotoxic effects of doxorubicin in tumor cells remains a major …

Recent advances in herbal combination nanomedicine for cancer: delivery technology and therapeutic outcomes

DM Anwar, M El-Sayed, A Reda, JY Fang… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: The use of herbal compounds in cancer therapy has great potential to promote
the efficacy of current cancer therapeutic strategies. Herbal compounds were successfully …

Lactate consumption via cascaded enzymes combined VEGF siRNA for synergistic anti‐proliferation and anti‐angiogenesis therapy of tumors

Y Tang, C Jia, Y Wang, W Wan, H Li… - Advanced …, 2021 - Wiley Online Library
Lactate, as the most abundant component with concentrations of 4–40 mm in tumors,
contributes to the regulation of metabolic pathways, angiogenesis, and immunosuppression …

Recent advances and future perspectives in the therapeutics of prostate cancer

GL Varaprasad, VK Gupta, K Prasad, E Kim… - … Hematology & Oncology, 2023 - Springer
Prostate cancer (PC) is one of the most common cancers in males and the fifth leading
reason of death. Age, ethnicity, family history, and genetic defects are major factors that …