RNA modifications, known as the “epitranscriptome”, represent a key layer of regulation that
influences a wide array of biological processes in mesenchymal stem cells (MSCs). These …

Mesenchymal stromal/stem cells (MSCs) are used in many studies due to their therapeutic
potential, including their differentiative ability and immunomodulatory properties. These cells …

The associations between inflammation and tissue regeneration are highly conserved
during the evolution of multicellular organisms [1]. Appropriate activation of immune cells is …

The impaired differentiation ability of resident cells and disordered immune
microenvironment in periodontitis pose a huge challenge for bone regeneration. Herein, we …

Mesenchymal stromal cells (MSCs) are used to treat infectious and immune diseases and
disorders; however, its mechanism (s) remain incompletely defined. Here we find that bone …

Undifferentiated, highly proliferative, clonogenic, and self-renewing dental stem cells have
paved the way for novel approaches to mending cleft palates, rebuilding lost jawbone and …

The jawbone, a unique structure in the human body, undergoes faster remodeling than other
bones due to the presence of stem cells and its distinct immune microenvironment. Long …

Dental pulp stem cells (DPSCs) have received a lot of attention as a regenerative medicine
tool with strong immunomodulatory capabilities. The excessive inflammatory response …

MSC-based therapeutic strategies have proven to be incredibly effective. Robust self-
renewal, multilineage differentiation, and potential for tissue regeneration and disease …

Conventional methods of stem cell therapy for tissue regeneration often face challenges,
such as poor cell viability and integration posttransplantation. To address this, we proposed …