Breast cancer in men
SH Giordano - New England Journal of Medicine, 2018 - Mass Medical Soc
Breast Cancer in Men Breast cancer in men accounts for about 1% of all breast cancers and
is mainly estrogen-receptor–positive. Few prospective studies of treatment in men have …
is mainly estrogen-receptor–positive. Few prospective studies of treatment in men have …
[HTML][HTML] Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention
NM Davis, M Sokolosky, K Stadelman, SL Abrams… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Abstract The EGFR/PI3K/PTEN/Akt/mTORC1/GSK-3 pathway plays prominent roles in
malignant transformation, prevention of apoptosis, drug resistance and metastasis. The …
malignant transformation, prevention of apoptosis, drug resistance and metastasis. The …
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
Background BRCA1 and, more commonly, BRCA2 mutations are associated with increased
risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of …
risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of …
Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and …
AB Spurdle, FJ Couch, MT Parsons, L McGuffog… - Breast Cancer …, 2014 - Springer
Introduction The distribution of histopathological features of invasive breast tumors in
BRCA1 or BRCA2 germline mutation carriers differs from that of individuals with no known …
BRCA1 or BRCA2 germline mutation carriers differs from that of individuals with no known …
Genetic landscape of male breast cancer
FAB Campos, E Rouleau, GT Torrezan, DM Carraro… - Cancers, 2021 - mdpi.com
Simple Summary Male breast cancer is a rare disease, representing around 0.5% of the
malignances in men. Although they receive the same treatment as women with breast …
malignances in men. Although they receive the same treatment as women with breast …
[HTML][HTML] Characterization of the HER2 status in BRCA-mutated breast cancer: a single institutional series and systematic review with pooled analysis
G Tomasello, D Gambini, F Petrelli, J Azzollini… - Esmo Open, 2022 - Elsevier
Background Pathogenic variants (PVs) in BRCA1/2 genes account for∼ 6% of breast and
20% of ovarian cancers. Most breast tumors developed by BRCA1 carriers are triple …
20% of ovarian cancers. Most breast tumors developed by BRCA1 carriers are triple …
Male breast cancer: from molecular genetics to clinical management
M Pensabene, C Von Arx, M De Laurentiis - Cancers, 2022 - mdpi.com
Simple Summary Male breast cancer (MBC) is a rare disease. Genetic factors predispose to
male breast cancer. Germline and/or genetic and/or epigenetic alterations at the somatic …
male breast cancer. Germline and/or genetic and/or epigenetic alterations at the somatic …
Characterisation of male breast cancer: a descriptive biomarker study from a large patient series
MP Humphries, S Sundara Rajan, H Honarpisheh… - Scientific reports, 2017 - nature.com
Male breast cancer (MBC) is rare. We assembled 446 MBCs on tissue microarrays and
assessed clinicopathological information, together with data from 15 published studies …
assessed clinicopathological information, together with data from 15 published studies …
Gender-Specific Genetic Predisposition to Breast Cancer: BRCA Genes and Beyond
V Valentini, A Bucalo, G Conti, L Celli, V Porzio… - Cancers, 2024 - mdpi.com
Simple Summary The role of gender in oncology is an issue that is starting to be recognized
as being of extreme importance in the last few years. While breast cancer is commonly …
as being of extreme importance in the last few years. While breast cancer is commonly …