[HTML][HTML] An overview of oxidative stress, neuroinflammation, and neurodegenerative diseases

DM Teleanu, AG Niculescu, II Lungu, CI Radu… - International journal of …, 2022 - mdpi.com
Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

[HTML][HTML] Alzheimer's disease: an update and insights into pathophysiology

MB Abubakar, KO Sanusi, A Ugusman… - Frontiers in aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is an irreversible brain disorder associated with slow, progressive
loss of brain functions mostly in older people. The disease processes start years before the …

[HTML][HTML] NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's …

MW Park, HW Cha, J Kim, JH Kim, H Yang, S Yoon… - Redox biology, 2021 - Elsevier
Oxidative stress has been implicated in the pathogenesis of Alzheimer's disease (AD).
Mitochondrial dysfunction is linked to oxidative stress and reactive oxygen species (ROS) in …

[HTML][HTML] Amyloid beta in aging and Alzheimer's disease

U Sehar, P Rawat, AP Reddy, J Kopel… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), is a progressive neurodegenerative disease that affects behavior,
thinking, learning, and memory in elderly individuals. AD occurs in two forms, early onset …

Role of oxidative stress in depression

S Bhatt, AN Nagappa, CR Patil - Drug discovery today, 2020 - Elsevier
Highlights•The Reactive Oxygen Species have an utmost importance in progression of
Depression.•Depression is associated with lowered concentration of anti-oxidants in …

[HTML][HTML] Neuroprotective effect of SGLT2 inhibitors

A Pawlos, M Broncel, E Woźniak, P Gorzelak-Pabiś - Molecules, 2021 - mdpi.com
Patients with diabetes are at higher risk of cardiovascular diseases and cognitive
impairment. SGLT2 inhibitors (Empagliflozin, Canagliflozin, Dapagliflozin, Ertugliflozin …

[HTML][HTML] Oxidative stress: a key modulator in neurodegenerative diseases

A Singh, R Kukreti, L Saso, S Kukreti - Molecules, 2019 - mdpi.com
Oxidative stress is proposed as a regulatory element in ageing and various neurological
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …

Hazardous effects of chemical pesticides on human health–Cancer and other associated disorders

A Sabarwal, K Kumar, RP Singh - Environmental toxicology and …, 2018 - Elsevier
Poisoning from pesticides is a global public health problem and accounts for nearly 300,000
deaths worldwide every year. Exposure to pesticides is inevitable; there are different modes …

[HTML][HTML] Adult hippocampal neurogenesis in aging and Alzheimer's disease

KR Babcock, JS Page, JR Fallon, AE Webb - Stem cell reports, 2021 - cell.com
Cognitive deficits associated with Alzheimer's disease (AD) severely impact daily life for the
millions of affected individuals. Progressive memory impairment in AD patients is associated …

[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy

C Grinán-Ferré, A Bellver-Sanchis, V Izquierdo… - Ageing Research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …