Pharmacological evidence supporting a role for galanin in cognition and affect

CC Wrenn, JN Crawley - Progress in Neuro-Psychopharmacology and …, 2001 - Elsevier
Galanin is localized in brain pathways involved in both cognition and affect. 2. Galanin has
inhibitory actions on a variety of memory tasks including the Morris water maze, delayed …

Estrogen action in the regulation of cell proliferation, cell survival, and tumorigenesis in the rat anterior pituitary gland

TJ Spady, RD McComb, JD Shull - Endocrine, 1999 - Springer
Estrogens act as important regulators of cell proliferation, cell survival, and differentiation in
a variety of organ systems and tissues and have been implicated in the etiology of a variety …

Neuropeptides in hippocampus and cortex in transgenic mice overexpressing V717F β-amyloid precursor protein—initial observations

M Diez, J Koistinaho, K Kahn, D Games, T Hökfelt - Neuroscience, 2000 - Elsevier
Immunohistochemistry was used to analyse 18-and 26-month-old transgenic mice
overexpressing the human β-amyloid precursor protein under the platelet-derived growth …

Galanin in the brain: chemoarchitectonics and brain cartography—a historical review

DM Jacobowitz, A Kresse, G Skofitsch - Peptides, 2004 - Elsevier
We present a review of galanin in the brain from a historical perspective of the development
of “chemoarchitectonics” and “brain cartography” accomplished in the Histopharmacology …

The role of galanin as a multi-functional neuropeptide in the nervous system

D Wynick, SWN Thompson, SB McMahon - Current opinion in …, 2001 - Elsevier
The neuropeptide galanin is expressed developmentally in the DRG and is rapidly up-
regulated 120-fold after peripheral nerve section in the adult. The generation and study of …

Pituitary hypoplasia and lactotroph dysfunction in mice deficient for cyclin-dependent kinase-4

DS Moons, S Jirawatnotai, AF Parlow, G Gibori… - …, 2002 - academic.oup.com
The lactotroph undergoes dynamic regulation of cell cycle progression during pregnancy, as
well as throughout the development of the pituitary. We recently reported that female mice …

Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells

G Kusumawidjaja, H Kayed, N Giese… - Cancer biology & …, 2007 - Taylor & Francis
Basic transcription factor 3 (BTF3) acts as a transcription factor and modulator of apoptosis,
and is differentially expressed in colorectal cancer and glioblastomas. In the present study …

Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice

B Ahrén, G Pacini, D Wynick, N Wierup… - Endocrinology, 2004 - academic.oup.com
The neuropeptide galanin is expressed in sympathetic nerve terminals that surround islet
cells and inhibits insulin secretion. To explore its role for islet function, we studied mice with …

Galanin and galanin receptors

TP Iismaa, J Shine - Regulatory Peptides and Cognate Receptors, 1999 - Springer
The neuropeptide galanin was isolated in 1983 and subsequently shown to have a
widespread distribution in the central and peripheral nervous system of vertebrate and …

SAGE identification of gene transcripts with profiles unique to pluripotent mouse R1 embryonic stem cells

SV Anisimov, KV Tarasov, D Tweedie, MD Stern… - Genomics, 2002 - Elsevier
The identification of signals that regulate pluripotentiality and self-renewal is fundamental to
the understanding of stem cell biology. To quantify the functionally active genome of …