Induced pluripotent stem cell‐derived extracellular vesicles: A novel approach for cell‐free regenerative medicine
B Taheri, M Soleimani, S Fekri Aval… - Journal of Cellular …, 2019 - Wiley Online Library
In recent years, induced pluripotent stem cells (iPSCs) have been considered as a
promising approach in the field of regenerative medicine. iPSCs can be generated from …
promising approach in the field of regenerative medicine. iPSCs can be generated from …
Exosomes derived from induced pluripotent stem cells suppresses M2-type macrophages during pulmonary fibrosis via miR-302a-3p/TET1 axis
Y Zhou, Y Gao, W Zhang, Y Chen, M Jin… - International …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (PF) is a type of chronic lung disease. Here, we investigated
the effect of induced pluripotent stem cell (iPSC)-derived exosomes (iPSC-exosomes) on M2 …
the effect of induced pluripotent stem cell (iPSC)-derived exosomes (iPSC-exosomes) on M2 …
Anti-inflammatory drug candidates for prevention and treatment of cardiovascular diseases
Q Delbaere, N Chapet, F Huet, C Delmas, N Mewton… - Pharmaceuticals, 2023 - mdpi.com
Incidence and mortality rates for cardiovascular disease are declining, but it still remains a
major cause of morbidity and mortality. Drug treatments to slow the progression of …
major cause of morbidity and mortality. Drug treatments to slow the progression of …
[HTML][HTML] Safety and biodistribution of exosomes derived from human induced pluripotent stem cells
Z Gu, Z Yin, P Song, Y Wu, Y He, M Zhu… - … in Bioengineering and …, 2022 - frontiersin.org
As a new cell-free therapy, exosomes have provided new ideas for the treatment of various
diseases. Human induced pluripotent stem cells (hiPSCs) cannot be used in clinical trials …
diseases. Human induced pluripotent stem cells (hiPSCs) cannot be used in clinical trials …
Stem cell-derived extracellular vesicles for cancer therapy and tissue engineering applications
Recently, stem cells and their secretomes have attracted great attention in biomedical
applications, particularly extracellular vesicles (EVs). EVs are secretomes of cells for cell-to …
applications, particularly extracellular vesicles (EVs). EVs are secretomes of cells for cell-to …
Exosomes derived from MSC pre‐treated with oridonin alleviates myocardial IR injury by suppressing apoptosis via regulating autophagy activation
M Fu, D Xie, Y Sun, Y Pan, Y Zhang… - Journal of cellular …, 2021 - Wiley Online Library
This study aimed to investigate the molecular mechanisms underlying the role of bone
marrow mesenchymal stem cells (BMMSCs)‐derived exosomes in ischaemia/reperfusion …
marrow mesenchymal stem cells (BMMSCs)‐derived exosomes in ischaemia/reperfusion …
Tanshinone IIA improves cardiac function via regulating miR-499-5p dependent angiogenesis in myocardial ischemic mice
X Wang, C Wu - Microvascular Research, 2022 - Elsevier
Background/aims Myocardial ischemia-reperfusion injury leads to aggravated cardiac
remodeling and heart failure. After myocardial infarction (MI), angiogenesis plays a vital role …
remodeling and heart failure. After myocardial infarction (MI), angiogenesis plays a vital role …
[HTML][HTML] Stem cell therapy for diabetic foot ulcers: Theory and practice
DL Nalisa, M Moneruzzaman, GJ Changwe… - Journal of Diabetes …, 2022 - hindawi.com
Diabetic foot ulcers are associated with increases in limb amputation, morbidity, and
mortality. Recently, a stem cell application is emerging as promising adjuvant therapy. We …
mortality. Recently, a stem cell application is emerging as promising adjuvant therapy. We …
Different sourced extracellular vesicles and their potential applications in clinical treatments
L Bahmani, M Ullah - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) include a heterogeneous group of natural cell-derived
nanostructures that are increasingly regarded as promising biotherapeutic agents and drug …
nanostructures that are increasingly regarded as promising biotherapeutic agents and drug …
Differential effects of extracellular vesicles of lineage-specific human pluripotent stem cells on the cellular behaviors of isogenic cortical spheroids
Extracellular vesicles (EVs) contribute to a variety of signaling processes and the overall
physiological and pathological states of stem cells and tissues. Human induced pluripotent …
physiological and pathological states of stem cells and tissues. Human induced pluripotent …