Stem cell extracellular vesicles and their potential to contribute to the repair of damaged CNS cells
Neurological diseases and disorders are leading causes of death and disability worldwide.
Many of these pathologies are associated with high levels of neuroinflammation and …
Many of these pathologies are associated with high levels of neuroinflammation and …
A review of the potential of induced pluripotent stem cell-derived exosome as a novel treatment for male infertility
Exosomes are a subset of Extracellular vesicles (EVs) released by most cells in the body
and can play a significant role in the intercellular connection. Researchers today claim that …
and can play a significant role in the intercellular connection. Researchers today claim that …
[HTML][HTML] Induced pluripotent stem cell-based therapies for organ fibrosis
W Cheng, C Fan, Q Song, P Chen, H Peng… - … in Bioengineering and …, 2023 - frontiersin.org
Fibrotic diseases result in organ remodelling and dysfunctional failure and account for one-
third of all deaths worldwide. There are no ideal treatments that can halt or reverse …
third of all deaths worldwide. There are no ideal treatments that can halt or reverse …
[HTML][HTML] Utilization of human induced pluripotent stem cells for cardiac repair
The paracrine effect, mediated by chemical signals that induce a physiological response on
neighboring cells in the same tissue, is an important regenerative mechanism for stem cell …
neighboring cells in the same tissue, is an important regenerative mechanism for stem cell …
Induced pluripotent stem cells as natural biofactories for exosomes carrying miR-199b-5p in the treatment of spinal cord injury
J Li, Y Jing, F Bai, Y Wu, L Wang, Y Yan, Y Jia… - Frontiers in …, 2023 - frontiersin.org
Background: Induced pluripotent stem cells-derived exosomes (iPSCs-Exo) can effectively
treat spinal cord injury (SCI) in mice. But the role of iPSCs-Exo in SCI mice and its molecular …
treat spinal cord injury (SCI) in mice. But the role of iPSCs-Exo in SCI mice and its molecular …
[HTML][HTML] Engineered circulatory scaffolds for building cardiac tissue
S Huang, Y Yang, Q Yang, Q Zhao… - Journal of Thoracic …, 2018 - ncbi.nlm.nih.gov
Heart failure (HF) is the terminal state of cardiovascular disease (CVD), leading numerous
patients to death every year. Cardiac tissue engineering is a multidisciplinary field of …
patients to death every year. Cardiac tissue engineering is a multidisciplinary field of …
Repeated intravenous administration of hiPSC-MSCs enhance the efficacy of cell-based therapy in tissue regeneration
SJ Sun, F Li, M Dong, WH Liang, WH Lai, WI Ho… - Communications …, 2022 - nature.com
We seek to demonstrate whether therapeutic efficacy can be improved by combination of
repeated intravenous administration and local transplantation of human induced …
repeated intravenous administration and local transplantation of human induced …
Exosomes derived from induced cardiopulmonary progenitor cells alleviate acute lung injury in mice
L Xia, Y Xiao, W Jiang, X Yang, H Tao… - Acta Pharmacologica …, 2024 - nature.com
Cardiopulmonary progenitor cells (CPPs) constitute a minor subpopulation of cells that are
commonly associated with heart and lung morphogenesis during embryonic development …
commonly associated with heart and lung morphogenesis during embryonic development …
Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the HAND2-AS1/miR-17-5p/Mfn2 …
Q Li, Y Bu, H Shao, W Li, D Zhao, J Wang - BMC cardiovascular disorders, 2023 - Springer
Background The exosomes (exos) of bone marrow mesenchymal stem cells (BMSCs) play
an important therapeutic role in repairing myocardial injury. The purpose of this study was to …
an important therapeutic role in repairing myocardial injury. The purpose of this study was to …
[PDF][PDF] Exosome-derived long non-coding RNA ZFAS1 controls cardiac fibrosis in chronic kidney disease
Y Wang, X Cao, L Yan, Y Zheng, J Yu… - Aging (Albany …, 2021 - pdfs.semanticscholar.org
The incidence of chronic kidney disease (CKD) complicated with cardiovascular disease
(CVD) is increasing day by day. CVD complication is a significant risk factor for the …
(CVD) is increasing day by day. CVD complication is a significant risk factor for the …