Stem cell extracellular vesicles and their potential to contribute to the repair of damaged CNS cells

H Branscome, S Paul, P Khatkar, Y Kim… - Journal of Neuroimmune …, 2020 - Springer
Neurological diseases and disorders are leading causes of death and disability worldwide.
Many of these pathologies are associated with high levels of neuroinflammation and …

A review of the potential of induced pluripotent stem cell-derived exosome as a novel treatment for male infertility

K Sojoudi, H Azizi, T Skutella - Biotechnology and Genetic …, 2023 - Taylor & Francis
Exosomes are a subset of Extracellular vesicles (EVs) released by most cells in the body
and can play a significant role in the intercellular connection. Researchers today claim that …

[HTML][HTML] Induced pluripotent stem cell-based therapies for organ fibrosis

W Cheng, C Fan, Q Song, P Chen, H Peng… - … in Bioengineering and …, 2023 - frontiersin.org
Fibrotic diseases result in organ remodelling and dysfunctional failure and account for one-
third of all deaths worldwide. There are no ideal treatments that can halt or reverse …

[HTML][HTML] Utilization of human induced pluripotent stem cells for cardiac repair

C Fan, E Zhang, J Joshi, J Yang, J Zhang… - Frontiers in Cell and …, 2020 - frontiersin.org
The paracrine effect, mediated by chemical signals that induce a physiological response on
neighboring cells in the same tissue, is an important regenerative mechanism for stem cell …

Induced pluripotent stem cells as natural biofactories for exosomes carrying miR-199b-5p in the treatment of spinal cord injury

J Li, Y Jing, F Bai, Y Wu, L Wang, Y Yan, Y Jia… - Frontiers in …, 2023 - frontiersin.org
Background: Induced pluripotent stem cells-derived exosomes (iPSCs-Exo) can effectively
treat spinal cord injury (SCI) in mice. But the role of iPSCs-Exo in SCI mice and its molecular …

[HTML][HTML] Engineered circulatory scaffolds for building cardiac tissue

S Huang, Y Yang, Q Yang, Q Zhao… - Journal of Thoracic …, 2018 - ncbi.nlm.nih.gov
Heart failure (HF) is the terminal state of cardiovascular disease (CVD), leading numerous
patients to death every year. Cardiac tissue engineering is a multidisciplinary field of …

Repeated intravenous administration of hiPSC-MSCs enhance the efficacy of cell-based therapy in tissue regeneration

SJ Sun, F Li, M Dong, WH Liang, WH Lai, WI Ho… - Communications …, 2022 - nature.com
We seek to demonstrate whether therapeutic efficacy can be improved by combination of
repeated intravenous administration and local transplantation of human induced …

Exosomes derived from induced cardiopulmonary progenitor cells alleviate acute lung injury in mice

L Xia, Y Xiao, W Jiang, X Yang, H Tao… - Acta Pharmacologica …, 2024 - nature.com
Cardiopulmonary progenitor cells (CPPs) constitute a minor subpopulation of cells that are
commonly associated with heart and lung morphogenesis during embryonic development …

Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the HAND2-AS1/miR-17-5p/Mfn2 …

Q Li, Y Bu, H Shao, W Li, D Zhao, J Wang - BMC cardiovascular disorders, 2023 - Springer
Background The exosomes (exos) of bone marrow mesenchymal stem cells (BMSCs) play
an important therapeutic role in repairing myocardial injury. The purpose of this study was to …

[PDF][PDF] Exosome-derived long non-coding RNA ZFAS1 controls cardiac fibrosis in chronic kidney disease

Y Wang, X Cao, L Yan, Y Zheng, J Yu… - Aging (Albany …, 2021 - pdfs.semanticscholar.org
The incidence of chronic kidney disease (CKD) complicated with cardiovascular disease
(CVD) is increasing day by day. CVD complication is a significant risk factor for the …