Established and new rotavirus vaccines: a comprehensive review for healthcare professionals

V Vetter, RC Gardner, S Debrus… - Human vaccines & …, 2022 - Taylor & Francis
Robust scientific evidence related to two rotavirus (RV) vaccines available worldwide
demonstrates their significant impact on RV disease burden. Improving RV vaccination …

Genetic engineering strategy for generating a stable dsRNA virus vector using a virus-like codon-modified transgene

Y Kanai, M Onishi, Y Yoshida, T Kotaki… - Journal of …, 2023 - Am Soc Microbiol
Deletion or truncation of transgenes encoded in RNA virus vectors frequently occur. Genetic
instability of transgenes is the primary obstacle to establishing RNA virus vectors as …

[HTML][HTML] The Economic Value of Rotavirus Vaccination When Optimally Implemented in a High-Income Country

B Standaert - Vaccines, 2023 - mdpi.com
Rotavirus vaccination was introduced in high-income countries starting in 2006, with no
recommendation for optimal implementation. Economic evaluations were presented before …

[HTML][HTML] Review of over 15 years postmarketing safety surveillance spontaneous data for the human rotavirus vaccine (Rotarix) on intussusception

T Singh, F Delannois, F Haguinet, LY Molo - Drug Safety, 2022 - Springer
Introduction Rotavirus (RV) is the most common cause of acute gastroenteritis in children< 5
years of age worldwide, and vaccination reduces the disease burden. Evidence from …

[HTML][HTML] Rotaviruses and noroviruses as etiological agents of acute intestinal diseases of Ukrainian children

SO Soloviov, TS Todosiichuk, OV Kovaliuk… - International Journal of …, 2022 - mdpi.com
(1) Background: Rotavirus and norovirus infections are the primary viral causes of childhood
diarrhea. In Ukraine, the diarrhea-linked infant mortality rate is low, but the number of …

[HTML][HTML] Defining the Recipe for an Optimal Rotavirus Vaccine Introduction in a High-Income Country in Europe

B Standaert, B Benninghoff - Viruses, 2022 - mdpi.com
Observational data over 15 years of rotavirus vaccine introduction in Belgium have indicated
that rotavirus hospitalisations in children aged< 5 years plateaued at a higher level than …

[HTML][HTML] Explaining the formation of a plateau in rotavirus vaccine impact on rotavirus hospitalisations in Belgium

B Standaert, D Strens, M Raes, B Benninghoff - Vaccine, 2022 - Elsevier
Background Observational data on the reduction in hospitalisations after rotavirus vaccine
introduction in Belgium suggest that vaccine impact plateaued at an unexpectedly high …

[HTML][HTML] The economic impact of the introduction of universal rotavirus vaccination on rotavirus gastroenteritis related hospitalisations in children in Ireland

A Murphy, A Kirby, F De Blasio - Vaccine, 2023 - Elsevier
Background Rotavirus gastroenteritis (RVGE), a vaccine preventable disease, remains a
common cause of severe gastroenteritis in children globally. Ireland introduced the universal …

[PDF][PDF] Rotavirus Infection in Neonates and Young Infants

P Shakya, B Adhikari, AS Nepal, P Pandey… - 2022 - academia.edu
Rotavirus is the primary cause of acute, frequently severe gastroenteritis among growing
premature neonates, young infants, and children under the age of five globally. It contains a …

Clinical characteristics, health care resource utilization and direct medical costs of Rotavirus hospitalizations in Spain (2013–2018)

J Arístegui, S Alfayate-Miguelez… - Human vaccines & …, 2022 - Taylor & Francis
Rotavirus (RV) is the most common cause of severe gastroenteritis (GE) in infants and
young children worldwide and is associated with a significant clinical and economic burden …