Pathogenesis and virulence of Candida albicans
JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …
Immunity to invasive fungal diseases
A Casadevall - Annual review of immunology, 2022 - annualreviews.org
Invasive fungal diseases are rare in individuals with intact immunity. This, together with the
fact that there are only a few species that account for most mycotic diseases, implies a …
fact that there are only a few species that account for most mycotic diseases, implies a …
[HTML][HTML] Mechanical overloading induces GPX4-regulated chondrocyte ferroptosis in osteoarthritis via Piezo1 channel facilitated calcium influx
S Wang, W Li, P Zhang, Z Wang, X Ma, C Liu… - Journal of advanced …, 2022 - Elsevier
Introductions Excessive mechanical stress is closely associated with cell death in various
conditions. Exposure of chondrocytes to excessive mechanical loading leads to a catabolic …
conditions. Exposure of chondrocytes to excessive mechanical loading leads to a catabolic …
Candida albicans can foster gut dysbiosis and systemic inflammation during HIV infection
SD Zaongo, J Ouyang, S Isnard, X Zhou… - Gut …, 2023 - Taylor & Francis
Candida albicans (C. albicans) is a ubiquitous fungal commensal component of the human
microbiota, and under certain circumstances, such as during an immunocompromised state …
microbiota, and under certain circumstances, such as during an immunocompromised state …
[PDF][PDF] Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion
J Westman, J Plumb, A Licht, M Yang, S Allert… - Cell reports, 2022 - cell.com
Candida albicans is both a commensal and an opportunistic fungal pathogen. Invading
hyphae of C. albicans secrete candidalysin, a pore-forming peptide toxin. To prevent cell …
hyphae of C. albicans secrete candidalysin, a pore-forming peptide toxin. To prevent cell …
Candidalysins are a new family of cytolytic fungal peptide toxins
Candidalysin is the first cytolytic peptide toxin identified in any human fungal pathogen.
Candidalysin is secreted by Candida albicans and is critical for driving infection and host …
Candidalysin is secreted by Candida albicans and is critical for driving infection and host …
Exploring the inflammatory pathogenesis of colorectal cancer
AA Khalyfa, S Punatar, R Aslam, A Yarbrough - Diseases, 2021 - mdpi.com
Colorectal cancer is one of the most commonly diagnosed cancers worldwide. Traditionally,
mechanisms of colorectal cancer formation have focused on genetic alterations including …
mechanisms of colorectal cancer formation have focused on genetic alterations including …
[HTML][HTML] Is Candida albicans a contributor to cancer? A critical review based on the current evidence
X Wang, W Zhang, W Wu, S Wu, A Young… - Microbiological Research, 2023 - Elsevier
The association between Candida albicans (C. albicans) and cancer has been noticed for
decades. Whether C. albicans infection is a complication of cancer status or as a contributor …
decades. Whether C. albicans infection is a complication of cancer status or as a contributor …
Candidalysin: Connecting the pore forming mechanism of this virulence factor to its immunostimulatory properties
CM Russell, JA Rybak, J Miao, BM Peters… - Journal of Biological …, 2023 - ASBMB
Candida albicans is a deadly pathogen responsible for millions of mucosal and systemic
infections per year. The pathobiology of C. albicans is largely dependent on the damaging …
infections per year. The pathobiology of C. albicans is largely dependent on the damaging …
Evaluation of a novel synthetic peptide derived from cytolytic mycotoxin candidalysin
PHO Cardoso, APA Boleti, PS Silva, LTH Mukoyama… - Toxins, 2022 - mdpi.com
The importance of neuroinflammation in neurology is becoming increasingly apparent. In
addition to neuroinflammatory diseases such as multiple sclerosis, the role of …
addition to neuroinflammatory diseases such as multiple sclerosis, the role of …