Osteoporosis is a chronic disease characterized by low bone mass caused by increased
bone turnover and impaired bone microarchitecture. In treatment, we use antiresorptive or …

Osteoporosis is caused by the disruption in homeostasis between bone formation and bone
resorption. Conventional management of osteoporosis involves systematic drug …

The restoration of bone defects caused by osteoporosis remains a challenge for surgeons.
Strontium ranelate has been applied in preventative treatment approaches due to the …

Adipose stem cells (ASCs) are a crucial element in bone tissue engineering (BTE). They are
easy to harvest and isolate, and they are available in significative quantities, thus offering a …

X-ray attenuation ability, otherwise known as radiopacity of a material, could be indisputably
tagged as the central and decisive parameter that produces contrast in an X-ray image …

Bone is the most studied tissue in the field of tissue regeneration. Even though it has intrinsic
capability to regenerate upon injury, several pathologies and injuries could hamper the …

Titanium (Ti) and its alloys are commonly used implant materials in orthopedics due to their
good corrosion resistance, mechanical properties, and biocompatibility. However, the …

Bone defect disease causes damage to people's lives and property, and how to effectively
promote bone regeneration is still a big clinical challenge. Most of the current repair …

Bone generally displays a high intrinsic capacity to regenerate. Nonetheless, large osseous
defects sometimes fail to heal. The treatment of such large segmental defects still represents …

The efficient healing of critical-sized bone defects using synthetic biomaterial-based
strategies is promising but remains challenging as it requires the development of …