Histamine Receptors: Ex Vivo Functional Studies Enabling the Discovery of Hits and Pathways
A Seldeslachts, S Peigneur, J Tytgat - Membranes, 2023 - mdpi.com
Histamine receptors (HRs) are G-protein-coupled receptors involved in diverse responses
triggered by histamine release during inflammation or by encounters with venomous …
triggered by histamine release during inflammation or by encounters with venomous …
[HTML][HTML] Voltage sensitivities and deactivation kinetics of histamine H3 and H4 receptors
K Sahlholm, J Nilsson, D Marcellino, K Fuxe… - Biochimica et Biophysica …, 2012 - Elsevier
Agonist potency at some neurotransmitter receptors has been shown to be regulated by
voltage, a mechanism which has been suggested to play a crucial role in the regulation of …
voltage, a mechanism which has been suggested to play a crucial role in the regulation of …
The clozapine metabolite N-desmethylclozapine displays variable activity in diverse functional assays at human dopamine D2 and serotonin 5-HT1A receptors
P Heusler, LB Slot, A Tourette, S Tardif… - European journal of …, 2011 - Elsevier
N-desmethylclozapine (NDMC or norclozapine) is the major active metabolite of the
antipsychotic clozapine in humans. The activity of NDMC differs from clozapine at a number …
antipsychotic clozapine in humans. The activity of NDMC differs from clozapine at a number …
Electrophysiology-Based Investigations of G Protein-Coupled Receptor Pharmacology
R Ågren - 2020 - search.proquest.com
G protein-coupled receptors (GPCRs) constitute targets for~ 34% of approved drugs. The
muscarinic acetylcholine M 2 receptor (M 2 R) activates G protein-coupled receptor inward …
muscarinic acetylcholine M 2 receptor (M 2 R) activates G protein-coupled receptor inward …