Increasing evidence suggests that abnormal cerebral glucose metabolism is largely present
in Alzheimer's disease (AD). The brain utilizes glucose as its main energy source and a …

Recently, the pandemic outbreak of a novel coronavirus, officially termed as severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), indicated by a pulmonary infection in …

This study investigated the inhibitory mechanism of quercetin in acetylcholinesterase
(AChE) and its neuroprotective effects on β-amyloid25–35-induced oxidative stress injury in …

The beneficial effects of vitamin D (vit D) on central nervous system disorders have been
suggested. In the current research, the protective effects of vit D on learning and memory …

Background There is no doubt that Alzheimer's disease (AD) is one of the greatest threats
facing mankind today. Within the next few decades, Acetylcholinesterase inhibitors (AChEIs) …

Amyloid-β, tau pathology, and biomarkers of neurodegeneration make up the core
diagnostic biomarkers of Alzheimer disease (AD). However, these proteins represent only a …

Diabetes is a chronic progressive metabolic disease caused by insulin deficiency or insulin
resistance. In spite of the availability of several antihyperglycaemics, there is a need for the …

Background: Diabetes mellitus and Alzheimer's disease are two common diseases that
majorly affect the elderly population. Patients in both cases are increasing day by day. They …

Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by a
progressive decline in cognitive performance and memory formation. The present study was …

Glycogen synthase kinase 3β (GSK-3β) catalyses the hyperphosphorylation of tau protein in
the Alzheimer's disease (AD) pathology. A series of novel thieno [3, 2-c] pyrazol-3-amine …