The success of cancer immunotherapy relies on the knowledge of the tumor
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …

The immune system has evolved to protect the host from a universe of pathogenic microbes
that are themselves constantly evolving. The immune system also helps the host eliminate …

The skin is a barrier site that is exposed to a wide variety of potential pathogens. As in other
organs, pathogens that invade the skin are recognized by pattern-recognition receptors …

Given the chronic inflammatory nature of Parkinson's disease (PD), T cell immunity may be
important for disease onset. Here, we performed single-cell transcriptome and TCR …

Contact allergies are complex diseases, and one of the important challenges for public
health and immunology. The German 'Federal Institute for Risk Assessment'hosted an …

Natural killer T (NKT) cells are important regulatory lymphocytes that have been shown in
mouse studies, to have a crucial role in promoting immunity to tumours, bacteria and viruses …

The complex tumor microenvironment is a most important factor in cancer development. The
biological microenvironment is composed of a variety of barriers including the extracellular …

Triptolide is a predominant active component of Triptergium wilfordii Hook. F, which has
been used for the treatment of cancers and autoimmune diseases such as rheumatoid …

Exosomes are secreted extracellular vesicles (EVs) that carry micro RNAs and other factors
to reprogram cancer cells and tissues affected by cancer. Exosomes are exchanged …

Vaccines, one of the most effective and powerful public health measures, have saved
countless lives over the past century and still have a tremendous global impact. As an …